For the patient with diabetes mellitus, which microvascular complication of the blood vessel structure may occur? Select all that apply. One, some, or all responses may be correct.
Nephropathy
Neuropathy
Peripheral vascular disease
Cerebral vascular disease
Retinopathy
Correct Answer : A,B,E
Choice A: Nephropathy
Diabetic nephropathy is a common microvascular complication of diabetes mellitus. It is characterized by damage to the small blood vessels in the kidneys, leading to progressive kidney disease. The condition is often identified by the presence of protein in the urine (proteinuria) and can progress to end-stage renal disease if not managed properly. The primary mechanism involves hyperglycemia-induced damage to the glomeruli, the filtering units of the kidneys. This damage results in increased permeability and eventual scarring, impairing kidney function. Effective management of blood glucose levels and blood pressure is crucial in preventing or slowing the progression of diabetic nephropathy.
Choice B: Neuropathy
Diabetic neuropathy refers to nerve damage caused by chronic high blood sugar levels. It is another significant microvascular complication of diabetes. This condition can affect various types of nerves, including sensory, motor, and autonomic nerves. Symptoms may include pain, tingling, numbness, and loss of sensation, particularly in the extremities. Diabetic neuropathy can lead to severe complications such as foot ulcers and infections, which may necessitate amputation. The pathophysiology involves hyperglycemia-induced oxidative stress and inflammation, leading to nerve damage. Tight glycemic control and regular monitoring are essential in managing diabetic neuropathy.

Choice E: Retinopathy
Diabetic retinopathy is a leading cause of blindness among adults with diabetes. This microvascular complication involves damage to the small blood vessels in the retina, the light-sensitive tissue at the back of the eye. There are two main types: non-proliferative and proliferative retinopathy. Non-proliferative retinopathy is characterized by microaneurysms, hemorrhages, and exudates, while proliferative retinopathy involves the growth of new, fragile blood vessels that can bleed and cause retinal detachment. The primary cause is prolonged hyperglycemia, which damages the retinal blood vessels. Regular eye examinations and good glycemic control are vital in preventing and managing diabetic retinopathy.
Choice C: Peripheral Vascular Disease
Peripheral vascular disease (PVD) is not classified as a microvascular complication but rather a macrovascular one. It involves the narrowing or blockage of the blood vessels outside the heart and brain, primarily affecting the arteries in the legs. PVD is associated with atherosclerosis, where plaque builds up in the arterial walls, leading to reduced blood flow. Symptoms include leg pain, cramping, and ulcers. While PVD is a significant concern for individuals with diabetes, it is not considered a microvascular complication.
Choice D: Cerebral Vascular Disease
Cerebral vascular disease, which includes conditions such as stroke and transient ischemic attacks (TIAs), is also a macrovascular complication rather than a microvascular one. It involves the blood vessels supplying the brain and is primarily caused by atherosclerosis and hypertension. Diabetes increases the risk of cerebral vascular disease due to its association with other risk factors like high blood pressure and dyslipidemia. However, it is not classified as a microvascular complication.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["B","C","D"]
Explanation
Choice A Reason:
Administering 0.45% NS (normal saline) at 50 mL/hr is not appropriate for a client with SIADH. This hypotonic solution can exacerbate the condition by increasing the water retention and further diluting the serum sodium levels, worsening hyponatremia. Instead, fluid restriction and hypertonic saline (such as 3% saline) are typically used to manage SIADH.
Choice B Reason:
Obtaining daily weight is crucial in managing SIADH. Daily weights help monitor fluid retention and detect any sudden changes in body weight, which can indicate worsening fluid overload or effective treatment. Accurate weight measurements are essential for assessing the client’s fluid balance and guiding treatment decisions.
Choice C Reason:
Maintaining seizure precautions is necessary for clients with SIADH because severe hyponatremia can lead to neurological symptoms, including seizures. Implementing seizure precautions helps ensure the client’s safety and allows for prompt intervention if a seizure occurs.
Choice D Reason:
Administering 3% saline as ordered is appropriate for treating severe hyponatremia in SIADH. Hypertonic saline helps increase serum sodium levels and reduce the risk of neurological complications. It must be administered carefully and under close monitoring to avoid rapid correction of sodium levels, which can lead to osmotic demyelination syndrome.
Choice E Reason:
Encouraging fluid intake is not appropriate for clients with SIADH. Fluid restriction is a key component of managing SIADH to prevent further dilution of serum sodium levels. Encouraging fluid intake would counteract this goal and worsen the client’s condition.
Correct Answer is D
Explanation
Choice A reason: No change to the heparin rate is not appropriate in this scenario. The normal range for PTT is generally between 25 to 35 seconds. However, for a client on heparin therapy, the target PTT is typically 1.5 to 2.5 times the normal range, which would be approximately 60 to 80 seconds. Since the client’s PTT is only 25 seconds, it indicates that the blood is clotting too quickly, and the heparin dose is insufficient.
Choice B reason: Decreasing the heparin rate would further reduce the anticoagulant effect, which is not advisable given the current PTT of 25 seconds. Lowering the heparin rate could increase the risk of thrombus formation and worsen the deep vein thrombosis (DVT) condition.
Choice C reason: Stopping heparin and starting warfarin is not an immediate solution. Warfarin takes several days to achieve its full anticoagulant effect, and during this transition period, the client would be at risk of clot formation. Heparin provides immediate anticoagulation, which is crucial in the acute management of DVT.
Choice D reason: Increasing the heparin rate is the correct action. The current PTT of 25 seconds is below the therapeutic range for a client on heparin therapy. Increasing the heparin rate will help achieve the desired anticoagulant effect, prolonging the PTT to the target range of 60 to 80 seconds.
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