A nurse is reviewing the medical history of a client who has myasthenia gravis and is asking about starting neostigmine. The nurse should identify which of the following client conditions as a potential contraindication for cholinesterase inhibitor therapy?

Cataracts

Hypertension

Hypothyroidism

Peptic ulcer disease

Answer and Explanation

The Correct Answer is D

A. Cataracts are not a contraindication for cholinesterase inhibitors like neostigmine.

B. Hypertension is not a direct contraindication for cholinesterase inhibitor therapy, although caution may be exercised depending on the overall health status of the client.

C. Hypothyroidism is not contraindicated for cholinesterase inhibitors; however, it should be managed appropriately.

D. Peptic ulcer disease is a significant contraindication for cholinesterase inhibitors like neostigmine because these medications can increase gastric secretions and motility, potentially exacerbating ulcer conditions and leading to complications.

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Correct Answer is C

Explanation

A. Sargramostim is a granulocyte-macrophage colony-stimulating factor (GM-CSF) used to stimulate the production of white blood cells but is not specifically indicated for anemia.

B. Filgrastim is a granulocyte colony-stimulating factor (G-CSF) that increases white blood cell counts and is not used for treating anemia.

C. Epoetin is an erythropoiesis-stimulating agent that stimulates red blood cell production, making it the appropriate choice for treating chemotherapy-induced anemia.

D. Romiplostim is a thrombopoietin receptor agonist used to treat thrombocytopenia (low platelet count) and is not indicated for anemia.

A. Ganciclovir B. Amphotericin B C. Azithromycin D. Nitrofurantoin

Correct Answer is D

Explanation

A. Ganciclovir: Ganciclovir is an antiviral medication used primarily to treat viral infections such as cytomegalovirus (CMV), not bacterial infections like UTIs.

B. Amphotericin B: Amphotericin B is an antifungal agent used to treat serious fungal infections, not bacterial UTIs.

C. Azithromycin: Azithromycin is an antibiotic that is effective against a broad range of bacterial infections but is not commonly used for treating recurrent UTIs.

D. Nitrofurantoin: Nitrofurantoin is an antibiotic commonly used to prevent and treat recurrent lower urinary tract infections due to its efficacy in targeting the bacteria that typically cause UTIs.

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A nurse is reviewing the medical history of a client who has myasthenia gravis and is asking about starting neostigmine. The nurse should identify which of the following client conditions as a potential contraindication for cholinesterase inhibitor therapy?

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Correct Answer is C

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Correct Answer is D

Explanation

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