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 A nurse is reviewing the medical history of a client who has myasthenia gravis and is asking about starting neostigmine. The nurse should identify which of the following client conditions as a potential contraindication for cholinesterase inhibitor therapy?

A.

Cataracts

B.

Hypertension

C.

Hypothyroidism

D.

Peptic ulcer disease

Answer and Explanation

The Correct Answer is D

A. Cataracts are not a contraindication for cholinesterase inhibitors like neostigmine.

 

B. Hypertension is not a direct contraindication for cholinesterase inhibitor therapy, although caution may be exercised depending on the overall health status of the client.

 

C. Hypothyroidism is not contraindicated for cholinesterase inhibitors; however, it should be managed appropriately.

 

D. Peptic ulcer disease is a significant contraindication for cholinesterase inhibitors like neostigmine because these medications can increase gastric secretions and motility, potentially exacerbating ulcer conditions and leading to complications.

 


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Related Questions

Correct Answer is B

Explanation

A. A decrease in the amount of gastric acid production: Alosetron is not used to decrease gastric acid production. This effect is more associated with medications such as proton pump inhibitors or H2 blockers.

B. A decrease in the frequency of defecation: Alosetron is used to treat irritable bowel syndrome with diarrhea (IBS-D) by reducing bowel movement frequency and improving stool consistency.

C. An increase in gastric motility: Alosetron works by decreasing intestinal motility, which helps reduce diarrhea, not by increasing it.

D. An increase in the absorption of water into the intestine: Alosetron does not specifically increase water absorption into the intestine. Its primary effect is slowing intestinal transit to reduce diarrhea.

Correct Answer is D

Explanation

A. Cataracts are not a contraindication for cholinesterase inhibitors like neostigmine.

B. Hypertension is not a direct contraindication for cholinesterase inhibitor therapy, although caution may be exercised depending on the overall health status of the client.

C. Hypothyroidism is not contraindicated for cholinesterase inhibitors; however, it should be managed appropriately.

D. Peptic ulcer disease is a significant contraindication for cholinesterase inhibitors like neostigmine because these medications can increase gastric secretions and motility, potentially exacerbating ulcer conditions and leading to complications.

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