Paget's disease is most commonly observed in which age group?

The typical pattern of bone involvement in Paget's disease is characterized by patchy areas of increased bone density (osteosclerosis) and disorganized bone formation. These areas of abnormal bone remodeling result in structurally weak and misshapen bones.

a. Uniform increase in bone density throughout the skeleton: This pattern of bone density is not characteristic of Paget's disease. The condition involves localized areas of increased density rather than uniform changes.

b. Focal areas of bone demineralization scattered throughout the skeleton: This pattern of bone demineralization is more characteristic of osteoporosis, not Paget's disease.

c. Diffuse increase in bone density with areas of focal bone loss: This pattern is not typical of Paget's disease. The condition primarily involves areas of increased bone density and disordered bone remodeling.

Paget's disease is a metabolic bone disorder that involves abnormal bone remodeling, leading to areas of increased bone density and disorganized bone formation. It is not a genetic disorder, autoimmune disease, or neurological disorder.

a. A genetic disorder characterized by abnormal bone density: While Paget's disease has a genetic component, it is not solely a genetic disorder. The condition involves both genetic and environmental factors.

b. An autoimmune disease affecting the joints and connective tissues: Paget's disease is not an autoimmune disease. It primarily affects bone structures, not joints and connective tissues.

d. A degenerative neurological disorder causing muscle weakness: Paget's disease is not a neurological disorder. It does not directly affect the nervous system or cause muscle weakness.