Screening at 24 weeks of gestation reveals that a pregnant woman has gestational diabetes mellitus (GDM). In planning her care, the nurse and the woman mutually agree that an expected outcome is to prevent injury to the fetus as a result of GDM. The nurse identifies that the fetus is at greatest risk for:

Choice A reason: Low birth weight is not a common complication of GDM, as the fetus tends to grow larger than normal due to the excess glucose and insulin in the blood. Low birth weight is more likely to occur in infants of mothers with preexisting diabetes or other conditions that affect placental function.

Choice B reason: Preterm birth is a possible complication of GDM, as the increased fetal size and the risk of maternal hypertension or infection may induce labor before term. However, it is not the greatest risk for the fetus, as preterm infants can survive with proper care and treatment.

Choice C reason: Macrosomia is the greatest risk for the fetus of a mother with GDM, as it is defined as a birth weight of more than 4000 g or 8 lb 13 oz. Macrosomia can cause difficulties during labor and delivery, such as shoulder dystocia, birth trauma, or cesarean birth. It can also increase the risk of neonatal hypoglycemia, jaundice, or respiratory distress.

Choice D reason: Congenital anomalies of the central nervous system are not a common complication of GDM, as they usually occur in the first trimester of pregnancy, before GDM is diagnosed or develops. Congenital anomalies are more likely to occur in infants of mothers with preexisting diabetes or other genetic or environmental factors.

Choice A reason: HSV-2 is a viral infection that causes genital herpes. It is transmitted through sexual contact and can cause painful blisters and ulcers in the genital area. The primary infection is usually the most severe and lasts for several weeks. After the primary infection, the virus remains dormant in the nerve cells and can reactivate periodically, causing recurrent episodes of genital herpes. The frequency and severity of the recurrences vary from person to person.

Choice B reason: HPV is a viral infection that causes genital warts and cervical cancer. It is transmitted through sexual contact and can infect the skin and mucous membranes of the genital area. The primary infection is often asymptomatic and may clear spontaneously or persist for years. HPV does not cause recurrent episodes of genital warts or cervical cancer, but it can increase the risk of developing these conditions over time.

Choice C reason: CMV is a viral infection that causes flu-like symptoms and can affect various organs. It is transmitted through bodily fluids such as saliva, urine, blood, and semen. The primary infection is usually mild and may go unnoticed. After the primary infection, the virus remains latent in the body and can reactivate in people with weakened immune systems, causing serious complications. CMV does not cause recurrent episodes of flu-like symptoms or organ damage, but it can worsen the condition of people with HIV or AIDS.

Choice D reason: HIV is a viral infection that causes acquired immunodeficiency syndrome (AIDS). It is transmitted through sexual contact, blood transfusion, or sharing of needles. The primary infection is often accompanied by flu-like symptoms and lasts for a few weeks. After the primary infection, the virus gradually destroys the immune system and makes the person vulnerable to opportunistic infections and cancers. HIV does not cause recurrent episodes of flu-like symptoms or AIDS, but it can progress to AIDS over time.