The client receives one dose of 200 mg of a medication. How much drug is in the body at 3 half-lives?
50
100
25
75
The Correct Answer is C
Here’s the step-by-step process:
After the first half-life (1 half-life), 50% of the initial drug is left.
200 mg → 100 mg (half is eliminated, 100 mg remains).
After the second half-life (2 half-lives), 50% of the remaining drug is eliminated again.
100 mg → 50 mg (half of 100 mg is eliminated, 50 mg remains).
After the third half-life (3 half-lives), 50% of the remaining drug is eliminated again.
50 mg → 25 mg (half of 50 mg is eliminated, 25 mg remains).
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
To determine if the client's dose is safe and therapeutic, we need to calculate the appropriate dosing range based on the client's weight and compare it with the ordered dose.
Client's weight: 45 kg
Ordered dose: 500 mg every 8 hours, which equals 1500 mg/day (500 mg × 3 doses).
Calculate the therapeutic range:
The dosing range in the Davis Drug Guide is 20 to 40 mg/kg/day. So, for this client, based on their weight of 45 kg:
Minimum dose: 20 mg × 45 kg = 900 mg/day
Maximum dose: 40 mg × 45 kg = 1800 mg/day
The ordered dose of 1500 mg/day falls within this range (900 mg/day to 1800 mg/day), which means it is safe and therapeutic for the client.
Correct Answer is ["12"]
Explanation
1. Convert the child's weight from pounds to kilograms:
There are approximately 2.2 pounds in 1 kilogram.
33 pounds / 2.2 pounds/kg = 15 kg (approximately)
2. Calculate the total milligrams of amoxicillin needed per dose:
The order is for 20 mg/kg/dose.
The child weighs 15 kg.
20 mg/kg * 15 kg = 300 mg
3. Determine the concentration of the amoxicillin suspension:
The label shows the concentration is 125 mg/5 mL.
4. Set up a proportion to find the volume (in mL) needed:
125 mg / 5 mL = 300 mg / x mL
5. Solve for x:
Cross-multiply: 125x = 300 * 5
125x = 1500
x = 1500 / 125
x = 12 mL
Answer: You will administer 12 mL per dose.
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