The nurse assisting with Phase 1 drug studies is talking with a woman who asks, "Why can't I participate in this study?" What would be the nurse's best response?

Women are more prone to adverse effects from medications.

Drugs pose a greater risk to women of reproductive age.

Drugs affect women differently than they affect men.

Drugs are tested only on men because they are stronger.

Answer and Explanation

The Correct Answer is B

Choice A rationale

It is not correct to say that women are more prone to adverse effects from medications than men. Adverse effects can vary based on individual responses, and gender is not the sole determinant.

Choice B rationale

Women of reproductive age are often excluded from early-phase drug trials due to the potential risks that experimental drugs could pose to developing fetuses. The reproductive risk needs to be carefully managed to avoid harm.

Choice C rationale

While it is true that drugs can affect women differently than men, this answer does not directly address the specific reason why women are excluded from Phase 1 studies, which is primarily due to the potential risks to reproductive health.

Choice D rationale

This is incorrect because drugs are not tested only on men because they are stronger. This statement is not scientifically accurate and does not reflect the principles of clinical trial design.

Nursing Test Bank

Quiz #1: RN Exams Pharmacology Exams Quiz #2: RN Exams Medical-Surgical Exams Quiz #3: RN Exams Fundamentals Exams Quiz #4: RN Exams Maternal-Newborn Exams Quiz #5: RN Exams Anatomy and Physiology Exams Quiz #6: RN Exams Obstetrics and Pediatrics Exams Quiz #7: RN Exams Fluid and Electrolytes Exams Quiz #8: RN Exams Community Health Exams Quiz #9: RN Exams Promoting Health across the lifespan Exams Quiz #10: RN Exams Multidimensional care Exams

Get 100+ Naxlex Exit Exams for $79 Try Naxlex NCLEX-RN (14 Day Free-Trial)

Naxlex Comprehensive Predictor Exams

Quiz #1: Naxlex RN Comprehensive online practice 2019 B with NGN Quiz #2: Naxlex RN Comprehensive Predictor 2023 Quiz #3: Naxlex RN Comprehensive Predictor 2023 Exit Exam A Quiz #4: Naxlex HESI Exit LPN Exam Quiz #5: Naxlex PN Comprehensive Predictor PN 2020 Quiz #6: Naxlex VATI PN Comprehensive Predictor 2020 Quiz #8: Naxlex PN Comprehensive Predictor 2023 - Exam 1 Quiz #10: Naxlex HESI PN Exit exam Quiz #11: Naxlex HESI PN EXIT Exam 2

Free Nursing Study Resources

Correct Answer is B

Explanation

Choice A rationale

Ethosuximide (Zarontin) is used to treat absence seizures and is not suitable for emergency control of status epilepticus. It primarily works by affecting the T-type calcium channels in the brain.

Choice B rationale

Diazepam (Valium) is used in the emergency control of status epilepticus due to its fast-acting anticonvulsant properties. It enhances the effect of the neurotransmitter GABA, leading to an inhibitory effect on neuronal activity.

Choice C rationale

Phenobarbital (Luminal) is a barbiturate used for long-term management of epilepsy but is less preferred for immediate emergency control of status epilepticus due to its slower onset of action.

Choice D rationale

Phenytoin (Dilantin) can be used for the maintenance treatment of seizures, but it is less effective for the immediate control of status epilepticus compared to benzodiazepines like diazepam.

A. True. B. False.

Correct Answer is A

Explanation

Choice A rationale

True. Xanthine derivatives like theophylline can cause serious adverse effects, including brain damage, when blood levels become too high. It is critical to monitor theophylline levels to prevent toxicity and associated neurological complications.

Choice B rationale

False. If xanthine levels remain within therapeutic ranges, the risk of brain damage is minimized. However, this statement is incorrect as it does not acknowledge the potential severity of the adverse effects linked to elevated theophylline levels.

View Question and Answer

Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.

Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today

The nurse assisting with Phase 1 drug studies is talking with a woman who asks, "Why can't I participate in this study?" What would be the nurse's best response?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A patient is admitted to the emergency department with severe recurrent convulsive seizures.Would the nurse expect to order for the use in emergency control of status epileptic?

Correct Answer is B

Explanation

The adverse effects of xanthene are related to the theophylline levels in the blood and include brain damage.

Correct Answer is A

Explanation

Order: 1000ml D5W at 120ml/hr. Available: Macro drop 15ml/hr. What is the drip factor in drops per minute?

Antitussive agents should be used with caution in patients who have a history of addiction.

When involved in phase III drug evaluation studies, what responsibilities would the nurse have?

The nurse is preparing to care for a patient who has myasthenia gravis.The nurse will be alert to symptoms affecting which body system in the patient?

A nurse is instructing a pregnant patient concerning the potential risk to her fetus from a pregnancy category B drug.What would the nurse inform the patient?

A nurse is caring for a six-year-old child who had surgery that morning.The child is awake and lying very still in bed.What should the nurse do?

The nurse admits a patient to the unit and learns the patient has recently been diagnosed with chronic renal failure but has not informed the primary care provider of this diagnosis.What is the nurse’s first priority?

A home care nurse administers oral morphine to the patient with cancer pain. When will the nurse expect the medication to reach peak activity?