The nurse assisting with Phase 1 drug studies is talking with a woman who asks, "Why can't I participate in this study?" What would be the nurse's best response?
Women are more prone to adverse effects from medications.
Drugs pose a greater risk to women of reproductive age.
Drugs affect women differently than they affect men.
Drugs are tested only on men because they are stronger.
The Correct Answer is B
Choice A rationale
It is not correct to say that women are more prone to adverse effects from medications than men. Adverse effects can vary based on individual responses, and gender is not the sole determinant.
Choice B rationale
Women of reproductive age are often excluded from early-phase drug trials due to the potential risks that experimental drugs could pose to developing fetuses. The reproductive risk needs to be carefully managed to avoid harm.
Choice C rationale
While it is true that drugs can affect women differently than men, this answer does not directly address the specific reason why women are excluded from Phase 1 studies, which is primarily due to the potential risks to reproductive health.
Choice D rationale
This is incorrect because drugs are not tested only on men because they are stronger. This statement is not scientifically accurate and does not reflect the principles of clinical trial design.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale
Pharmacodynamics is the study of how drugs affect the body, including the mechanisms of action and the relationship between drug concentration and effect. It does not describe the actions of the nurses in this context.
Choice B rationale
Pharmacotherapeutics involves the use of drugs to diagnose, treat, and prevent disease. The actions of the nurses in administering iodine, chemotherapy, and vaccines are examples of pharmacotherapeutics, as they are using drugs for therapeutic purposes.
Choice C rationale
Pharmacoeconomics is the study of the cost and value of drugs and therapies. It does not describe the actions of the nurses in administering medications.
Choice D rationale
Pharmacokinetics is the study of how the body absorbs, distributes, metabolizes, and excretes drugs. It does not describe the actions of the nurses in this context.
Correct Answer is A
Explanation
Choice A rationale
Asking the patient what time of day the medication is taken can help identify if taking it at a different time might alleviate sleep disturbances. SSRIs like sertraline can cause insomnia if taken later in the day.
Choice B rationale
Recommending a weekly dosage is inappropriate and could potentially disrupt the therapeutic effect. SSRIs should be taken daily, as prescribed.
Choice C rationale
Counseling the patient to take the medication at bedtime could worsen sleep disturbances, as sertraline may cause insomnia in some individuals. Timing should be adjusted based on patient response.
Choice D rationale
Suggesting a lower dose without consulting the provider may not address the issue effectively and could reduce the efficacy of the medication. Dosage adjustments should be made based on clinical assessment and provider recommendation.
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