The nurse assisting with Phase 1 drug studies is talking with a woman who asks, "Why can't I participate in this study?" What would be the nurse's best response?
Women are more prone to adverse effects from medications.
Drugs pose a greater risk to women of reproductive age.
Drugs affect women differently than they affect men.
Drugs are tested only on men because they are stronger.
The Correct Answer is B
Choice A rationale
It is not correct to say that women are more prone to adverse effects from medications than men. Adverse effects can vary based on individual responses, and gender is not the sole determinant.
Choice B rationale
Women of reproductive age are often excluded from early-phase drug trials due to the potential risks that experimental drugs could pose to developing fetuses. The reproductive risk needs to be carefully managed to avoid harm.
Choice C rationale
While it is true that drugs can affect women differently than men, this answer does not directly address the specific reason why women are excluded from Phase 1 studies, which is primarily due to the potential risks to reproductive health.
Choice D rationale
This is incorrect because drugs are not tested only on men because they are stronger. This statement is not scientifically accurate and does not reflect the principles of clinical trial design.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale
Giving ipecac with a glass of milk is not recommended. Milk can delay the emetic effect of ipecac and potentially interfere with its ability to induce vomiting. It is essential to follow proper guidelines for ipecac administration to ensure its effectiveness and safety.
Choice B rationale
Consulting a poison control center before administering ipecac is crucial. Poison control experts can provide specific recommendations based on the type and amount of substance ingested. Not all poisoning cases require ipecac, and its inappropriate use can cause more harm than good.
Choice C rationale
Ipecac fluid extract is significantly more potent than ipecac syrup and is not recommended for home use. The syrup form is standardized for safe administration in inducing vomiting, whereas the fluid extract can cause severe toxicity if used incorrectly.
Choice D rationale
The emetic effect of ipecac is not immediate. It typically takes about 20 to 30 minutes for vomiting to occur after administration. Providing patients and caregivers with accurate information about the onset of action is essential to avoid unnecessary anxiety.
Correct Answer is A
Explanation
Choice A rationale
Drawing up regular insulin first is recommended to avoid contamination of the vial with other types of insulin.
Choice B rationale
Incorrect, as it is standard practice to draw up regular insulin first to maintain purity and efficacy.
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