The nurse assisting with Phase 1 drug studies is talking with a woman who asks, "Why can't I participate in this study?" What would be the nurse's best response?
Women are more prone to adverse effects from medications.
Drugs pose a greater risk to women of reproductive age.
Drugs affect women differently than they affect men.
Drugs are tested only on men because they are stronger.
The Correct Answer is B
Choice A rationale
It is not correct to say that women are more prone to adverse effects from medications than men. Adverse effects can vary based on individual responses, and gender is not the sole determinant.
Choice B rationale
Women of reproductive age are often excluded from early-phase drug trials due to the potential risks that experimental drugs could pose to developing fetuses. The reproductive risk needs to be carefully managed to avoid harm.
Choice C rationale
While it is true that drugs can affect women differently than men, this answer does not directly address the specific reason why women are excluded from Phase 1 studies, which is primarily due to the potential risks to reproductive health.
Choice D rationale
This is incorrect because drugs are not tested only on men because they are stronger. This statement is not scientifically accurate and does not reflect the principles of clinical trial design.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A rationale
Ataxia is less commonly associated with opioids than other adverse effects.
Choice B rationale
Dysrhythmias are not typically associated with opioids.
Choice C rationale
Blurred vision isn't a major adverse effect of opioids.
Choice D rationale
Hypotension is a common adverse effect of opioid use and must be monitored.
Correct Answer is C
Explanation
Choice A rationale
Atorvastatin (Lipitor) does not decrease sitosterol. It mainly targets serum cholesterol and LDL levels to reduce cardiovascular risks.
Choice B rationale
Atorvastatin does not decrease campesterol. Its primary effect is on serum cholesterol and LDL levels, aiming to lower the risk of heart disease.
Choice C rationale
Atorvastatin effectively decreases serum cholesterol and LDL levels, which are the primary targets for reducing cardiovascular risks in patients with high cholesterol.
Choice D rationale
Atorvastatin lowers both serum cholesterol and LDL levels, not just serum cholesterol, making it effective in reducing overall cardiovascular risk.
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