When involved in phase III drug evaluation studies, what responsibilities would the nurse have?
Working with animals who are given experimental drugs.
Conducting research to determine the effectiveness of the drug.
Monitoring and observing patients closely for adverse effects.
Choosing appropriate patients to be involved in the study.
The Correct Answer is C
Choice A rationale
Working with animals is typically done in preclinical trials before phase I studies in humans and is not part of phase III drug evaluation studies.
Choice B rationale
Conducting research to determine the effectiveness of the drug is part of phase II studies. Phase III studies focus more on confirming effectiveness, monitoring side effects, and comparing it to commonly used treatments.
Choice C rationale
Monitoring and observing patients closely for adverse effects is a key responsibility in phase III drug evaluation studies. These studies involve a larger patient population to gather comprehensive safety and efficacy data.
Choice D rationale
Choosing appropriate patients to be involved in the study is primarily the responsibility of researchers and clinicians during the earlier phases of drug development, such as phase I and phase II studies.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A rationale
While maintaining patient confidentiality is crucial, it does not address the immediate medical needs of the patient with chronic renal failure. The primary concern should be addressing the health implications of their condition and ensuring proper care coordination.
Choice B rationale
Administering medications ordered immediately is essential, but it is not the first priority without knowing the patient's current status and medical history. The nurse needs to ensure that the medications prescribed are appropriate for a patient with chronic renal failure.
Choice C rationale
Providing teaching about chronic renal failure is important for long-term management but is not the first priority upon admission. Immediate medical needs and communication with the care team take precedence in this acute care setting.
Choice D rationale
Calling the admitting physician immediately is the first priority. The primary care provider needs to be aware of the patient's diagnosis of chronic renal failure to adjust treatment plans accordingly. Immediate communication ensures that all healthcare professionals are on the same page regarding the patient's care. .
Correct Answer is B
Explanation
Choice A rationale
Peripheral edema is more commonly associated with right-sided heart failure rather than left-sided. This is because right-sided heart failure leads to systemic venous congestion, causing fluid to accumulate in the peripheral tissues, particularly in the legs and ankles.
Choice B rationale
Pulmonary edema is a major concern in left-sided heart failure due to the inability of the left ventricle to effectively pump blood out to the systemic circulation. This results in blood backing up into the pulmonary veins, leading to fluid accumulation in the lungs.
Choice C rationale
Liver edema, or hepatomegaly, is more typically seen in right-sided heart failure, where the failure of the right ventricle causes blood to back up into the systemic circulation, affecting the liver and other organs.
Choice D rationale
Abdominal edema, or ascites, is also more associated with right-sided heart failure. This condition occurs due to increased pressure in the veins and capillaries, leading to fluid leakage into the abdominal cavity.
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