When involved in phase III drug evaluation studies, what responsibilities would the nurse have?
Working with animals who are given experimental drugs.
Conducting research to determine the effectiveness of the drug.
Monitoring and observing patients closely for adverse effects.
Choosing appropriate patients to be involved in the study.
The Correct Answer is C
Choice A rationale
Working with animals is typically done in preclinical trials before phase I studies in humans and is not part of phase III drug evaluation studies.
Choice B rationale
Conducting research to determine the effectiveness of the drug is part of phase II studies. Phase III studies focus more on confirming effectiveness, monitoring side effects, and comparing it to commonly used treatments.
Choice C rationale
Monitoring and observing patients closely for adverse effects is a key responsibility in phase III drug evaluation studies. These studies involve a larger patient population to gather comprehensive safety and efficacy data.
Choice D rationale
Choosing appropriate patients to be involved in the study is primarily the responsibility of researchers and clinicians during the earlier phases of drug development, such as phase I and phase II studies.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale
Sumatriptan does not cause vasodilation of peripheral blood vessels. Instead, it has vasoconstrictive properties.
Choice B rationale
Sumatriptan does not depress pain response in the central nervous system. Its primary action is on the cranial blood vessels.
Choice C rationale
Sumatriptan is a selective serotonin receptor agonist that causes vasoconstriction of cranial blood vessels, relieving migraine headaches.
Choice D rationale
Sumatriptan does not bind to acetylcholine receptors or prevent nerve transmission. It specifically targets serotonin receptors in cranial blood vessels.
Correct Answer is D
Explanation
Choice A rationale
Chronic Obstructive Pulmonary Disease (COPD) is a progressive disease characterized by obstructed airflow from the lungs. While related to respiratory health, it is distinct from tuberculosis.
Choice B rationale
Bronchiectasis is a condition involving the permanent enlargement of parts of the airways of the lung, often caused by infection or other lung conditions but is different from tuberculosis.
Choice C rationale
Emphysema is a chronic lung condition where the alveoli (air sacs) are damaged, leading to breathing difficulties. This condition is usually associated with smoking and is distinct from tuberculosis.
Choice D rationale
Consumption is an old term for tuberculosis, reflecting the wasting away (consuming) nature of the disease due to the progressive weight loss and weakness it causes.
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