The nurse has noted the high incidence of urinary tract obstructions of a variety of etiologies. Which individuals are at risk of developing urinary obstructions? (Select all that apply).

A. A 69-year-old female with anemia secondary to insufficient erythropoietin production: While anemia can occur due to chronic kidney disease, it does not directly cause urinary tract obstruction. The lack of erythropoietin affects red blood cell production, not urine flow.

B. A 70-year-old male with benign prostatic hyperplasia (BPH): BPH is a common cause of urinary obstruction in older men. The enlarged prostate compresses the urethra, leading to impaired urine outflow and increased risk of urinary retention.

C. A 58-year-old male with renal calculi: Kidney stones are a frequent cause of urinary tract obstruction. They can block the flow of urine in the ureters, renal pelvis, or bladder, leading to pain, hydronephrosis, and infection risk.

D. A 29-year-old female, pregnant for the first time: Pregnancy can cause urinary obstruction due to the enlarged uterus compressing the ureters, especially in the second and third trimesters, resulting in reduced urine flow and potential hydronephrosis.

E. A 28-year-old male with a neurogenic bladder secondary to spinal cord injury: Neurogenic bladder disrupts normal bladder function and control, which can lead to urinary retention and obstruction due to poor coordination of bladder muscle and sphincter activity.

F. A 43-year-old male with an acid-base imbalance secondary to malnutrition: While malnutrition can affect many organ systems, acid-base imbalance by itself is not a direct cause of urinary tract obstruction.

A. 60–89 mL/min/1.73m²: This range indicates mildly decreased GFR, often classified as Stage 2 chronic kidney disease. Renal function is still relatively preserved and not considered renal failure at this stage.

B. 30–59 mL/min/1.73m²: This reflects a moderate decrease in GFR, typically Stage 3 CKD. Although kidney function is significantly impaired, it is not yet categorized as renal failure.

C. 15–29 mL/min/1.73m²: This GFR indicates severe kidney impairment and is classified as Stage 4 CKD. While this stage shows significant dysfunction, renal failure is generally diagnosed at lower values.

D. <15 mL/min/1.73m²: A GFR below 15 signals end-stage renal disease (ESRD), also referred to as renal failure. At this stage, dialysis or kidney transplantation is usually necessary to sustain life.