The nurse is providing instructions about a client's new medications. How should the nurse explain the purpose of probenecid, a uricosuric drug?

Decreases pain and burning during urination.

Increases the strength of the urine stream.

Prevents the formation of kidney stones.

Promotes excretion of uric acid in the urine.

Answer and Explanation

The Correct Answer is D

Choice A reason: Decreasing pain and burning during urination is not the purpose of probenecid, which is a drug that lowers the level of uric acid in the blood. Probenecid is used to treat gout, a condition that causes painful inflammation of the joints due to the accumulation of uric acid crystals. Probenecid does not have any effect on the urinary tract or its symptoms.

Choice B reason: Increasing the strength of the urine stream is not the purpose of probenecid, which is a drug that increases the amount of uric acid in the urine. Probenecid works by blocking the reabsorption of uric acid by the kidneys, thus increasing its excretion. Probenecid does not have any effect on the bladder or its function.

Choice C reason: Preventing the formation of kidney stones is not the purpose of probenecid, which is a drug that can actually increase the risk of kidney stones. Probenecid increases the concentration of uric acid in the urine, which can lead to the formation of uric acid stones. The nurse should instruct the client to drink plenty of fluids and avoid foods high in purines, such as organ meats, seafood, and alcohol, to prevent kidney stones.

Choice D reason: Promoting excretion of uric acid in the urine is the purpose of probenecid, which is a drug that reduces the level of uric acid in the blood. Probenecid helps prevent gout attacks by preventing the buildup of uric acid crystals in the joints. The nurse should monitor the client's serum uric acid level, renal function, and urine output, and advise the client to take the medication with food to avoid stomach upset.

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Correct Answer is C

Explanation

Choice A reason: This is not the laboratory finding that indicates that the medication has been effective. Serum ammonia level of 30 Mcg/dL (17.62 mmol/L) is within the normal range for adults, and it does not reflect the effect of sodium polystyrene sulfonate. Sodium polystyrene sulfonate is a cation-exchange resin that binds to potassium in the intestine and removes it from the body through the stool. It does not affect the ammonia levels in the blood, which are influenced by the liver function and the urea cycle. The nurse should monitor the ammonia levels for any changes, but it is not the goal of the medication.

Choice B reason: This is not the laboratory finding that indicates that the medication has been effective. Hemoglobin level of 13.5 g/dL (135 g/L) is within the normal range for females, and it does not reflect the effect of sodium polystyrene sulfonate. Sodium polystyrene sulfonate does not affect the hemoglobin levels in the blood, which are determined by the number and size of red blood cells and the oxygen-carrying capacity of the blood. The nurse should monitor the hemoglobin levels for any changes, but it is not the goal of the medication.

Choice C reason: This is the laboratory finding that indicates that the medication has been effective. Serum potassium level of 3.8 mEq/L (3.8 mmol/L) is within the normal range for adults, and it indicates that the medication has lowered the potassium levels in the blood. Sodium polystyrene sulfonate is used to treat hyperkalemia, or high potassium levels, which can occur in AKI due to the impaired renal excretion of potassium. Hyperkalemia can cause cardiac arrhythmias, muscle weakness, and paralysis. The nurse should administer sodium polystyrene sulfonate as prescribed and check the serum potassium levels regularly to ensure that they are within the normal range.

Choice D reason: This is not the laboratory finding that indicates that the medication has been effective. Serum glucose level of 120 mg/dL (6.7 mmol/L) is slightly above the normal range for adults, and it does not reflect the effect of sodium polystyrene sulfonate. Sodium polystyrene sulfonate does not affect the glucose levels in the blood, which are influenced by the carbohydrate metabolism and the insulin secretion and action. The nurse should monitor the glucose levels for any changes, but it is not the goal of the medication.

A. Scratchy throat. B. Pupillary constriction. C. Bradycardia. D. Hypertension.

Correct Answer is A

Explanation

Choice A reason: This is the correct manifestation for the nurse to identify as a reason to stop the infusion. A scratchy throat may indicate an allergic reaction to piperacillin-tazobactam, which is a penicillin derivative. The client may also develop other signs of anaphylaxis, such as rash, itching, swelling, wheezing, or difficulty breathing. The nurse should stop the infusion immediately and notify the healthcare provider.

Choice B reason: This is not a correct manifestation for the nurse to identify as a reason to stop the infusion. Pupillary constriction is not a common or serious side effect of piperacillin-tazobactam. It may be caused by other factors, such as light exposure, medication use, or neurological conditions. The nurse should monitor the client's pupils for any changes, but it is not a reason to stop the infusion.

Choice C reason: This is not a correct manifestation for the nurse to identify as a reason to stop the infusion. Bradycardia, or a slow heart rate, is not a common or serious side effect of piperacillin-tazobactam. It may be caused by other factors, such as cardiac disorders, medication use, or vagal stimulation. The nurse should monitor the client's vital signs for any changes, but it is not a reason to stop the infusion.

Choice D reason: This is not a correct manifestation for the nurse to identify as a reason to stop the infusion. Hypertension, or high blood pressure, is not a common or serious side effect of piperacillin-tazobactam. It may be caused by other factors, such as stress, pain, or renal disorders. The nurse should monitor the client's blood pressure for any changes, but it is not a reason to stop the infusion.

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The nurse is providing instructions about a client's new medications. How should the nurse explain the purpose of probenecid, a uricosuric drug?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

The nurse is administering sodium polystyrene sulfonate to a client in acute kidney injury (AKI). Which laboratory finding indicates that the medication has been effective?

Correct Answer is C

Explanation

The nurse initiates an infusion of piperacillin-tazobactam for a client with a urinary tract infection. Five minutes into the infusion, the client reports not feeling well. Which client manifestation should the nurse identify as a reason to stop the infusion?

Correct Answer is A

Explanation

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