The nurse is providing teaching to a patient taking tetracycline. Which statement by the nurse is correct?
Avoid direct sunlight and tanning beds while on this medication.
Take the medication until you are feeling better.
Milk and cheese products result in increased levels of tetracycline.
Antacids taken with the medication help to reduce gastrointestinal distress.
The Correct Answer is A
Choice A reason: Tetracyclines, like doxycycline, cause photosensitivity by forming phototoxic compounds under UV light, leading to severe sunburn or rashes. Avoiding sunlight and tanning beds prevents skin damage, as tetracycline’s protein synthesis inhibition does not mitigate its phototoxic effects, making this the correct instruction.
Choice B reason: Taking tetracycline only until feeling better is incorrect, as incomplete treatment promotes bacterial resistance. Tetracyclines require a full course to eradicate infection, preventing survival of resistant mutants, which could worsen infections like acne or respiratory infections, making this an unsafe instruction.
Choice C reason: Milk and cheese reduce, not increase, tetracycline levels by chelating the drug, forming insoluble complexes that decrease absorption. This interaction lowers efficacy, requiring tetracycline to be taken away from dairy, making this statement incorrect for patient education.
Choice D reason: Antacids reduce tetracycline absorption by chelating with divalent cations (e.g., calcium, magnesium), forming insoluble complexes. This decreases efficacy, not gastrointestinal distress. Taking tetracycline away from antacids ensures proper absorption, making this statement incorrect and potentially harmful.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A reason: Fluconazole inhibits hepatic CYP2C9, which metabolizes warfarin, increasing warfarin’s plasma levels. This enhances its anticoagulant effect, inhibiting vitamin K-dependent clotting factors, leading to a higher risk of bleeding. Monitoring INR and bleeding signs is critical to prevent hemorrhage in patients on this combination.
Choice B reason: Warfarin does not decrease fluconazole’s antifungal efficacy. Fluconazole inhibits fungal ergosterol synthesis, and its action is unaffected by warfarin’s anticoagulant mechanism. The primary interaction is fluconazole’s effect on warfarin metabolism, not a reduction in fluconazole’s ability to treat fungal infections.
Choice C reason: Fluconazole increases, not reduces, warfarin’s anticoagulant effect by inhibiting CYP2C9, slowing warfarin metabolism. This leads to elevated warfarin levels, prolonging INR and increasing bleeding risk. Reduced anticoagulant action would occur with enzyme inducers, not inhibitors like fluconazole.
Choice D reason: Hypokalemia is not a known interaction between fluconazole and warfarin. Fluconazole’s side effects include hepatotoxicity, and warfarin affects clotting, but neither significantly alters potassium levels. Electrolyte imbalances are more associated with diuretics or amphotericin B, not this drug combination.
Correct Answer is B
Explanation
Choice A reason: Albuterol is a short-acting beta-2 agonist (SABA), with effects lasting 4-6 hours, while salmeterol is a long-acting beta-2 agonist (LABA), lasting up to 12 hours. This statement reverses their durations, making it incorrect, as albuterol is used for acute relief, not maintenance.
Choice B reason: Albuterol, a SABA, acts within minutes and lasts 4-6 hours, ideal for acute asthma relief. Salmeterol, a LABA, has a slower onset (20-30 minutes) and lasts 12 hours, used for maintenance. This pharmacodynamic difference in duration makes this the correct statement.
Choice C reason: Salmeterol’s effects last up to 12 hours, not 3-4 hours, and albuterol’s duration is 4-6 hours, not 12 hours. This statement inaccurately describes their pharmacodynamic profiles, as salmeterol is long-acting and albuterol is short-acting, making it incorrect.
Choice D reason: Albuterol’s rapid onset (within minutes) makes it ideal for acute asthma attacks, while salmeterol’s slow onset (20-30 minutes) makes it unsuitable for acute relief. This statement is incorrect, as albuterol, not salmeterol, is the first-line rescue medication for asthma exacerbations.
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