Thinking about aneurysms and atherosclerosis, what effect does atherosclerosis have on the development of an aneurysm?

Atherosclerosis causes ischemia of the intima

Atherosclerosis erodes the vessel wall

It increases nitric oxide

It obstructs the vessel

Answer and Explanation

The Correct Answer is B

A. Atherosclerosis causes ischemia of the intima: While atherosclerosis can affect the intima (the inner layer of the blood vessel), it primarily leads to plaque formation and vessel wall changes rather than causing ischemia directly in the intima. Ischemia typically refers to reduced blood supply to tissues.

B. Atherosclerosis erodes the vessel wall: Atherosclerosis leads to the formation of plaques that can erode and weaken the vessel wall over time. This weakening can create areas of localized dilation, leading to the development of aneurysms. The disruption of the structural integrity of the vessel wall due to atherosclerosis is a key factor in the formation of aneurysms.

C. It increases nitric oxide: Atherosclerosis is associated with impaired endothelial function, which typically results in reduced production of nitric oxide rather than an increase. Nitric oxide is a vasodilator that helps maintain vascular health, and its decrease contributes to vascular dysfunction.

D. It obstructs the vessel: While atherosclerosis can lead to vascular obstruction through plaque buildup, the direct relationship between atherosclerosis and aneurysm formation is more about the weakening and erosion of the vessel wall rather than simply obstructing it. Obstruction can lead to ischemia, but it is not the primary mechanism leading to aneurysm development.

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Correct Answer is D

Explanation

A. Hypoventilation causes hypocapnia: Hypoventilation leads to inadequate removal of carbon dioxide (CO₂), resulting in hypercapnia rather than hypocapnia. This occurs because decreased ventilation reduces gas exchange efficiency, allowing CO₂ to accumulate in the blood, which can cause respiratory acidosis.

B. Hypoventilation causes alkalosis: Hypoventilation leads to respiratory acidosis rather than alkalosis. When ventilation is insufficient, CO₂ builds up in the bloodstream, leading to an increase in hydrogen ion concentration and a subsequent drop in blood pH. This is commonly seen in conditions like chronic obstructive pulmonary disease (COPD), neuromuscular disorders, and opioid overdose.

C. Hyperventilation causes acidosis: Hyperventilation results in excessive elimination of CO₂, leading to a decrease in hydrogen ion concentration and an increase in blood pH, causing respiratory alkalosis rather than acidosis. Acidosis occurs when CO₂ retention leads to an increase in hydrogen ion concentration, which is the opposite of what happens with hyperventilation.

D. Hyperventilation causes hypocapnia: Hyperventilation leads to an excessive exhalation of CO₂, causing a reduction in blood CO₂ levels (hypocapnia). This can result in respiratory alkalosis, leading to symptoms such as dizziness, lightheadedness, tingling sensations, and even syncope. It is often seen in conditions like anxiety, panic attacks, fever, or high-altitude exposure.

A. Septal B. Restrictive C. Infiltrative D. Hypertrophic

Correct Answer is B

Explanation

A. Septal: Septal cardiomyopathy typically refers to abnormalities in the interventricular septum and does not specifically address the rigidity and noncompliance of the myocardium that affects diastolic filling.

B. Restrictive: Restrictive cardiomyopathy is characterized by a rigid and noncompliant myocardium that impedes ventricular filling during diastole. This results in elevated pressures in the ventricles and may lead to heart failure symptoms due to poor filling capacity.

C. Infiltrative: Infiltrative cardiomyopathy involves the deposition of abnormal substances (such as amyloid or sarcoid) within the myocardial tissue, which can lead to stiffness. While this may contribute to restrictive physiology, "restrictive" is the more precise term for the condition described.

D. Hypertrophic: Hypertrophic cardiomyopathy is characterized by an abnormal thickening of the heart muscle, particularly the left ventricle. While this condition can affect diastolic filling, it is primarily due to muscle hypertrophy rather than rigidity and noncompliance of the myocardium.

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Thinking about aneurysms and atherosclerosis, what effect does atherosclerosis have on the development of an aneurysm?

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Naxlex Comprehensive Predictor Exams

What have you learned about ventilation?

Correct Answer is D

Explanation

Myocardium is rigid and noncompliant, impeding ventricular filling and raising pressures during diastole is which form of cardiomyopathy?

Correct Answer is B

Explanation

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