Tissue damage in pancreatitis is initially triggered by:

Choice C reason: Limiting pancreatic secretion is the primary reason for making patients with acute pancreatitis NPO and using gastric suctioning. By reducing the stimulation of the pancreas, the inflammation and autodigestion of pancreatic tissue can be minimized, aiding in the healing process.
Choice A reason: Preventing abdominal distention is a secondary benefit of making patients NPO, but it is not the primary reason for this intervention in acute pancreatitis.
Choice B reason: Preventing mechanical obstruction of the intestine is not the main goal of making patients NPO in acute pancreatitis. This condition primarily affects the pancreas, not the intestines.
Choice D reason: Preventing hyperglycemia associated with loss of insulin secretion is not the primary reason for making patients NPO in acute pancreatitis. While hyperglycemia can occur in severe cases, the main focus is on reducing pancreatic stimulation.

Choice A reason:
As mentioned earlier, infusion reactions are common with Amphotericin B, including symptoms like fever and chills. Therefore, recognizing that these reactions occur is correct and indicates a proper understanding of the medication's effects.
Choice B reason:
Rapid administration of Amphotericin B is incorrect because it increases the risk of severe side effects. The infusion should be slow to ensure patient safety, indicating that the student needs further teaching on this point. Thus, this choice is incorrect and suggests a misunderstanding.
Choice C reason:
Frequent rotation of the IV site or the use of a central line is standard practice to minimize the risk of phlebitis. This practice is correct and shows that the student understands how to manage the complications associated with Amphotericin B infusion.
Choice D reason:
Amphotericin B's primary use is to treat systemic fungal infections. This is a correct statement, reflecting an accurate understanding of the drug's purpose and does not require further teaching.