What is encephalitis and what best describes the most common cause of encephalitis?

A. Clinical manifestations: hematuria (urine is smoky, brown tinged): Hematuria is a hallmark sign of acute glomerulonephritis. The smoky or cola-colored urine results from red blood cells leaking through the damaged glomeruli, often seen in post-infectious cases.

B. Clinical manifestations: oliguria: Decreased urine output is common due to impaired glomerular filtration. Oliguria reflects reduced kidney function, which contributes to fluid retention, hypertension, and accumulation of waste products.

C. Treatment: Antibiotics, corticosteroids, cytotoxic agents, anticoagulants: Depending on the cause and severity, treatment may include antibiotics for infection, corticosteroids or cytotoxic agents for inflammation, and anticoagulants if there's risk of thrombosis due to nephrotic syndrome features.

D. Treatment: Prescription dose ibuprofen: NSAIDs like ibuprofen are generally avoided in glomerulonephritis because they can reduce renal perfusion and worsen kidney injury, especially in patients already experiencing compromised kidney function.

E. Clinical manifestations: Proteinuria that exceeds 3–5g/day with albumin: This level of proteinuria is characteristic of nephrotic syndrome, not acute glomerulonephritis. While proteinuria may be present, it is typically moderate and not in the nephrotic range.

A. 60–89 mL/min/1.73m²: This range indicates mildly decreased GFR, often classified as Stage 2 chronic kidney disease. Renal function is still relatively preserved and not considered renal failure at this stage.

B. 30–59 mL/min/1.73m²: This reflects a moderate decrease in GFR, typically Stage 3 CKD. Although kidney function is significantly impaired, it is not yet categorized as renal failure.

C. 15–29 mL/min/1.73m²: This GFR indicates severe kidney impairment and is classified as Stage 4 CKD. While this stage shows significant dysfunction, renal failure is generally diagnosed at lower values.

D. <15 mL/min/1.73m²: A GFR below 15 signals end-stage renal disease (ESRD), also referred to as renal failure. At this stage, dialysis or kidney transplantation is usually necessary to sustain life.