Which are the early (prodromal) clinical manifestations of hepatitis. (Select all that apply).
Itching
Vomiting
Fatigue
Jaundice
Hyperalgia (increased sensitivity to pain)
Correct Answer : B,C,E
A. Itching: Pruritus typically develops during the icteric phase of hepatitis when bilirubin accumulates in the tissues. It is not considered an early or prodromal symptom but occurs later as jaundice becomes evident.
B. Vomiting: Nausea and vomiting are common prodromal symptoms of hepatitis due to liver inflammation and its impact on digestion. These gastrointestinal symptoms often occur before jaundice or other late signs become apparent.
C. Fatigue: Fatigue is one of the most frequently reported early symptoms of hepatitis. It results from the body's immune response and reduced liver function and may begin days or weeks before jaundice or dark urine appears.
D. Jaundice: Jaundice typically marks the transition to the icteric phase of hepatitis and follows the prodromal phase. It appears as liver dysfunction progresses and bilirubin accumulates in the bloodstream and tissues.
E. Hyperalgia (increased sensitivity to pain): Increased pain sensitivity, particularly in the upper right quadrant, can occur early in hepatitis due to liver inflammation. This symptom may accompany general malaise and precedes more visible signs like jaundice.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Androgens (sex hormones): These are produced in the zona reticularis of the adrenal cortex. They contribute to the development of secondary sex characteristics and have a minor role compared to gonadal hormones.
B. Glucocorticoids (cortisol): Cortisol is synthesized in the zona fasciculata of the adrenal cortex. It regulates metabolism, immune responses, and the stress response, making it a key adrenal cortical hormone.
C. Epinephrine: This hormone is produced by the adrenal medulla, not the cortex. It plays a major role in the fight-or-flight response, increasing heart rate and blood glucose levels during stress.
D. Mineralocorticoids (aldosterone): Aldosterone is produced in the zona glomerulosa of the adrenal cortex. It is essential for sodium retention, potassium excretion, and blood pressure regulation.
Correct Answer is A
Explanation
The adrenal cortex is vital for life because it produces key hormones such as cortisol, aldosterone, and androgens. Cortisol helps regulate metabolism, stress responses, and immune function. Aldosterone maintains sodium and potassium balance, crucial for blood pressure and fluid regulation. Without these hormones, the body cannot sustain essential physiological processes.
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