What is the antidote for Warfarin (Coumadin)?
Vitamin K
Protamine sulfate
Narcan
Flumazenil
The Correct Answer is A
Choice A reason: Warfarin inhibits vitamin K-dependent blood clotting factors, prolonging coagulation. Vitamin K reverses this by restoring factor synthesis in the liver, normalizing clotting. Administered orally or intravenously, it counteracts warfarin’s anticoagulant effect in cases of overdose or bleeding, making this the correct antidote.
Choice B reason: Protamine sulfate is the antidote for heparin, not warfarin. It binds to heparin, neutralizing its anticoagulant effect by forming an inactive complex. Warfarin acts via a different mechanism (vitamin K inhibition), so protamine sulfate is ineffective, making this choice incorrect for warfarin overdose.
Choice C reason: Narcan (naloxone) reverses opioid overdoses by competitively binding to opioid receptors, restoring respiration. It has no effect on warfarin’s anticoagulant mechanism, which involves vitamin K-dependent clotting factors, making this choice irrelevant and incorrect for treating warfarin toxicity.
Choice D reason: Flumazenil reverses benzodiazepine overdoses by antagonizing their sedative effects at GABA receptors. It does not affect warfarin’s inhibition of clotting factor synthesis, which requires vitamin K to reverse. This makes flumazenil incorrect for managing warfarin-related bleeding or toxicity.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A reason: Cluster C personality disorders include dependent, avoidant, and obsessive-compulsive disorders, characterized by anxious and fearful behaviors. Dependent personality disorder involves excessive reliance on others, driven by fear of abandonment, fitting the anxious profile of cluster C, making this the correct choice.
Choice B reason: Borderline personality disorder belongs to cluster B, marked by dramatic, emotional, and erratic behaviors. It involves impulsivity and unstable relationships, not the anxious-fearful traits of cluster C, making this choice incorrect for the specified cluster.
Choice C reason: Antisocial personality disorder is part of cluster B, characterized by dramatic and erratic behaviors, including disregard for others’ rights. It lacks the anxious-fearful characteristics of cluster C, focusing instead on impulsivity and aggression, making this choice incorrect.
Choice D reason: Paranoid personality disorder is in cluster A, defined by odd and eccentric behaviors, such as pervasive distrust. It does not align with the anxious-fearful traits of cluster C, making this choice incorrect for the nurse’s discussion.
Correct Answer is C
Explanation
Choice A reason: Insulin glargine is a long-acting insulin with an onset of 1–2 hours, providing basal coverage for 24 hours. It does not act rapidly to control postprandial glucose, unlike rapid-acting insulins, making this choice incorrect for the question.
Choice B reason: Insulin detemir is a long-acting insulin with an onset of 1–2 hours, used for steady glucose control. It lacks the rapid onset (<15 minutes) required for immediate postprandial glucose management, making this choice incorrect.
Choice C reason: Insulin aspart is a rapid-acting insulin analog with an onset of 10–15 minutes, peaking in 1–3 hours. It mimics the body’s insulin response to meals, effectively controlling postprandial glucose, making this the correct choice.
Choice D reason: Regular insulin has an onset of 30–60 minutes, slower than rapid-acting insulins. It is used for short-term glucose control but does not meet the <15-minute onset criterion, making this choice incorrect.
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