What is the definition of selective toxicity in relation to anti-infectives?
The ability of an anti-infective completely eliminate all microorganisms from the host's body.
The ability of an article to the host while targeting microorganisms.
The ability of an anti-infective to kill or inhibit the growth of microorganisms without causing harm to the host
The ability of an anti-infective to target specific microorganisms without affecting other microorganisms
The Correct Answer is C
Rationale:
A. This option is incorrect because complete elimination of all microorganisms is not typically achievable or desirable, as some microorganisms are beneficial.
B. While this statement is partially correct, it does not fully encompass the definition of selective toxicity, which emphasizes the balance of efficacy and safety.
C. Selective toxicity refers to the ability of an anti-infective to kill or inhibit the growth of microorganisms without causing harm to the host. This principle is fundamental in developing effective antimicrobial agents that target pathogens while minimizing toxicity to human cells.
D. This option implies a focus on targeting specific microorganisms, which is related but not the complete definition of selective toxicity, as it also involves not harming the host.
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Related Questions
Correct Answer is C
Explanation
A. Nephrotoxicity is a serious adverse effect of aminoglycosides that often require immediate discontinuation of the drug to prevent further damage.
B. Ototoxicity is a serious adverse effect of aminoglycosides that often require immediate discontinuation of the drug to prevent further damage.
C. Nausea is a common side effect of many medications, including aminoglycosides, but it typically does not necessitate discontinuation of treatment unless it is severe or persistent.
D. Vertigo can also be related to ototoxic effects and may require discontinuation depending on severity and persistence.
Correct Answer is B
Explanation
A. This option misrepresents critical concentration; it focuses on absorption rather than therapeutic efficacy.
B. The critical concentration refers to the minimum concentration of a medication in the blood needed to achieve the desired therapeutic effect. This concentration is essential to ensure that the medication is effective in treating the condition.
C. While the maximum concentration can relate to safety, critical concentration specifically concerns the minimum required for effectiveness.
D. This choice suggests an optimal concentration, which is different from the minimum concentration needed to achieve therapeutic effects.
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