What is the definition of selective toxicity in relation to anti-infectives?
The ability of an anti-infective completely eliminate all microorganisms from the host's body.
The ability of an article to the host while targeting microorganisms.
The ability of an anti-infective to kill or inhibit the growth of microorganisms without causing harm to the host
The ability of an anti-infective to target specific microorganisms without affecting other microorganisms
The Correct Answer is C
Rationale:
A. This option is incorrect because complete elimination of all microorganisms is not typically achievable or desirable, as some microorganisms are beneficial.
B. While this statement is partially correct, it does not fully encompass the definition of selective toxicity, which emphasizes the balance of efficacy and safety.
C. Selective toxicity refers to the ability of an anti-infective to kill or inhibit the growth of microorganisms without causing harm to the host. This principle is fundamental in developing effective antimicrobial agents that target pathogens while minimizing toxicity to human cells.
D. This option implies a focus on targeting specific microorganisms, which is related but not the complete definition of selective toxicity, as it also involves not harming the host.
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Related Questions
Correct Answer is C
Explanation
A. Rash is generally a mild adverse effect and does not indicate a severe reaction.
B. Nausea and vomiting are common side effects but not classified as severe reactions.
C. Ototoxicity is a severe adverse reaction associated with aminoglycoside therapy, potentially leading to hearing loss and balance issues. Monitoring for this side effect is crucial during treatment.
D. Headache can occur but is not considered a severe adverse reaction compared to ototoxicity.
Correct Answer is B
Explanation
A. While monitoring vital signs is important, it is not the first step in the antibiotic administration process.
B. Performing a culture and sensitivity test to identify the specific pathogen and its susceptibility is essential before administering a broad-spectrum antibiotic, as this ensures that the chosen antibiotic will be effective against the identified infection.
C. Administering the antibiotic immediately without obtaining a specimen sample may lead to ineffective treatment and can hinder identifying the causative agent later.
D. While consulting with the healthcare provider for appropriate dosage is important, it should follow the identification of the specific organism.
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