What is the primary pathophysiological process that occurs in disseminated intravascular coagulation (DIC)?

Decreased production of clotting factors

Impaired platelet function

Excessive activation of clotting factors and widespread clot formation

Excessive platelet production

Answer and Explanation

The Correct Answer is C

A.   DIC is not characterized by decreased production of clotting factors. Instead, it involves consumption of clotting factors due to widespread activation of coagulation.
B.   While platelet dysfunction may occur in DIC due to consumption and depletion of platelets, the primary pathophysiological process in DIC is the activation of clotting factors and formation of blood clots throughout the vasculature.
C.   Excessive activation of clotting factors and widespread clot formation is the primary pathophysiological process in DIC. This leads to the formation of numerous small blood clots throughout the body's blood vessels, resulting in organ dysfunction and potentially life-threatening complications.

D. Excessive platelet production is not a characteristic feature of DIC. Instead, platelets are consumed and depleted as they are incorporated into the blood clots formed during the
coagulation cascade in DIC.

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Correct Answer is D

Explanation

A. Hemoglobin A1C level is not typically assessed in patients with sickle cell anemia as it is primarily used to monitor long-term blood sugar control in individuals with diabetes mellitus.
B. While appetite may be relevant to the overall health of the patient, it is not the priority assessment in a patient with sickle cell anemia.
C. Reflexes may be assessed during the physical examination, but they are not the priority assessment in a patient with sickle cell anemia.
D. Vaccination history is the priority assessment in a patient with sickle cell anemia because individuals with sickle cell disease are at increased risk of infections, particularly from
encapsulated bacteria. Therefore, ensuring that the patient is up-to-date on vaccinations, including pneumococcal and meningococcal vaccines, is crucial for preventing serious infections.

A. Vitamin C B. Physical exercise C. Chemotherapy D. Antibiotics

Correct Answer is C

Explanation

A. Vitamin C is not known to cause bone marrow suppression. In fact, it is essential for the proper function of the immune system and the production of collagen.
B. Physical exercise does not cause bone marrow suppression. Regular exercise can have positive effects on bone health and overall well-being.
C. Chemotherapy, which is used to treat cancer, can cause bone marrow suppression as a side effect. It affects rapidly dividing cells, including those in the bone marrow responsible for producing blood cells.
D. Some antibiotics, such as certain types of penicillins and sulfonamides, can rarely cause bone marrow suppression as a side effect. However, this is not a common effect of all antibiotics.

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What is the primary pathophysiological process that occurs in disseminated intravascular coagulation (DIC)?

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Naxlex Comprehensive Predictor Exams

During an outpatient well visit with a patient who has sickle cell anemia, you make it PRIORITY to assess the patient's?

Correct Answer is D

Explanation

Which of the following can cause bone marrow suppression?

Correct Answer is C

Explanation

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