When educating a patient about Lorazepam (Ativan), the nurse should advise against the concurrent use of which substance?

The correct answer is: a. Right route, c. Right dose, d. Right person, e. Right documentation, f. Right medication.

Choice A: Right route

The right route ensures that the medication is administered via the correct method, such as oral, intravenous, or intramuscular. This is crucial because different routes can affect the medication’s absorption and effectiveness. Administering medication via the wrong route can lead to ineffective treatment or even harm the patient.

Choice B: Right to refuse

While patients do have the right to refuse medication, this is not one of the five main rights of medication administration. The five main rights focus on the correct administration process to ensure patient safety and effective treatment.

Choice C: Right dose

The right dose ensures that the patient receives the correct amount of medication. Administering too much or too little can lead to adverse effects or ineffective treatment. This right involves verifying the prescribed dose and measuring it accurately.

Choice D: Right person

The right person ensures that the medication is given to the correct patient. This is typically verified using two identifyers, such as the patient’s name and date of birth, to prevent medication errors.

Choice E: Right documentation

The right documentation involves accurately recording the administration of the medication. This includes noting the time, dose, route, and any observations. Proper documentation is essential for maintaining accurate medical records and ensuring continuity of care.

Choice F: Right medication

The right medication ensures that the correct drug is given to the patient. This involves checking the medication label against the doctor’s order to prevent errors. Administering the wrong medication can have serious consequences.

Choice A reason: This is correct. The liver is the main organ responsible for drug metabolism. The enzymes that the body uses to metabolize drugs are present throughout the body but are most abundant in the liver. The liver can transform drugs into more polar and water-soluble compounds, which can then be excreted by the kidneys or the biliary system.

Choice B reason: This is incorrect. The lungs are not primarily responsible for drug metabolism, although they can play a minor role in some cases. The lungs can metabolize some drugs that are inhaled, such as anesthetics, or drugs that circulate through the pulmonary blood vessels, such as propranolol. However, the lungs have a lower capacity and a lower variety of enzymes than the liver.

Choice C reason: This is incorrect. The heart is not responsible for drug metabolism, although it can be affected by it. The heart is the organ that pumps blood throughout the body, delivering oxygen and nutrients to the tissues and organs. The heart can be influenced by the pharmacokinetics and pharmacodynamics of drugs, which are the processes of drug absorption, distribution, metabolism, and excretion, and the effects of drugs on the body, respectively.

Choice D reason: This is incorrect. The kidney is not primarily responsible for drug metabolism, although it is important for drug excretion. The kidney is the organ that filters the blood and removes waste products and excess fluid as urine. The kidney can excrete drugs that are water-soluble or that are not reabsorbed by the tubules. The kidney can also metabolize some drugs, such as aspirin, but to a lesser extent than the liver.