Which antitumor drug has a dual role of being an antibiotic?

Methotrexate

Antiestrogens

Corticosteroid

Doxorubicin (Doxil)

Answer and Explanation

The Correct Answer is D

Choice A rationale: Incorrect. Methotrexate is a chemotherapy drug and an immunosuppressant but not an antibiotic. It inhibits the metabolism of folic acid, which is necessary for cell replication, but it does not have antibiotic properties.

Choice B rationale: Incorrect. Antiestrogens are a class of drugs used to treat hormone-sensitive cancers like breast cancer by blocking the effects of estrogen. They are not antibiotics and do not have antimicrobial properties.

Choice C rationale: Incorrect. Corticosteroids are used in cancer treatment primarily to reduce inflammation and manage side effects of chemotherapy, such as nausea and allergic reactions. They have immunosuppressive properties but are not antibiotics.

Choice D rationale: Correct. Doxorubicin (Doxil) is an antitumor drug that also has antibiotic properties. It belongs to the anthracycline class of chemotherapy drugs and works by intercalating DNA, disrupting the replication and transcription processes, leading to cell death. Doxorubicin was originally derived from the bacterium Streptomyces peucetius, which imparts its antibiotic properties.

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Correct Answer is C

Explanation

A. “Do you think you and your daughter may have time to go shopping for a wig between now and the time you begin treatment?”

This option recognizes the patient's concern about hair loss and offers a practical suggestion for preparing for it. It shows empathy and support by involving a family member in the process of coping with potential hair loss.

B. “Most patients just wear a hat or turban and just let their hair grow back following treatment.”

This statement provides an alternative approach to dealing with hair loss by suggesting the use of head coverings like hats or turbans. It emphasizes the temporary nature of the hair loss during treatment.

C. “I would be less concerned about cosmetic changes that you may experience and be more concerned about treating the cancer.”

This option encourages the patient to prioritize the cancer treatment over cosmetic concerns, emphasizing the importance of addressing the underlying health issue. It offers a supportive and empathetic perspective.

D. “Just pray about it.”

This option suggests relying on prayer as a sole coping mechanism, which may not address the patient's emotional concerns effectively. While spirituality and prayer can be important for some individuals, it's essential to provide practical and emotional support as well.

E. “Keep a positive attitude. Just wait until your treatment begins to before you become concerned

about losing your hair, after all, you may not experience hair loss.”

This statement encourages a positive attitude and suggests delaying concerns about hair loss until after treatment has begun. While maintaining a positive outlook is beneficial, it's also important to acknowledge and address the patient's current concerns and provide information about potential side effects.

A. Restrict the client’s intake of fluids. B. Premedicate the client with morphine. C. Stay with the client during the first 15 minutes of the infusion. D. Assess the client for the development of ototoxicity.

Correct Answer is C

Explanation

A. Restrict the client’s intake of fluids.

Fluid restriction is not a standard intervention during the administration of monoclonal antibodies.

B. Premedicate the client with morphine.

Morphine is not a standard premedication for monoclonal antibody infusions. Premedication may be used in some cases, but the specific medications used depend on the patient's individual needs and the nature of the monoclonal antibody being administered.

C. Stay with the client during the first 15 minutes of the infusion.

The rationale for staying with the client during the initial part of the infusion is to monitor for any immediate hypersensitivity reactions or infusion-related adverse events, which can sometimes occur early in the infusion process. This allows the nurse to respond promptly if the client experiences any adverse reactions.

D. Assess the client for the development of ototoxicity.

Ototoxicity (hearing loss) is not a common concern with monoclonal antibody infusions. The focus of assessment during the infusion is primarily on immediate hypersensitivity reactions and other infusion-related adverse events.

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Which antitumor drug has a dual role of being an antibiotic?

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Naxlex Comprehensive Predictor Exams

Correct Answer is C

Explanation

When administering an intravenous infusion of monoclonal antibodies, it is most important for the nurse to implement which of the following interventions?

Correct Answer is C

Explanation

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