Which class of antimicrobials does not cause hepatotoxicity?
Cephalosporin
Sulfonamide
Penicillin
Fluroquinolone
The Correct Answer is C
A. Cephalosporins are a class of antibiotics that can, in some cases, cause liver enzyme elevations and hepatotoxicity. While not all cephalosporins are associated with significant liver toxicity, there have been reports of liver dysfunction with some members of this class.
B. Sulfonamides can also cause hepatotoxicity, particularly in certain individuals. They are known to occasionally lead to liver enzyme elevations and even more severe liver damage in susceptible patients.
C. Penicillins are generally considered safe regarding hepatotoxicity; however, there can be rare instances of liver enzyme elevation associated with some penicillin derivatives, particularly in cases of prolonged use or in patients with existing liver disease. Nonetheless, they are not commonly associated with significant hepatotoxicity.
D. Fluoroquinolones can cause liver toxicity, although it is relatively rare. Some fluoroquinolones have been associated with elevated liver enzymes and other hepatic issues.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Primary hypertension, also known as essential hypertension, is characterized by high blood pressure that does not have a known secondary cause. It accounts for the majority of hypertension cases and is thought to result from a combination of genetic, environmental, and lifestyle factors.
B. While treatment is important for all forms of hypertension to prevent complications, this statement is somewhat misleading. The term "essential" in primary hypertension refers to the lack of a specific identifiable cause, not that it is necessarily more critical to treat than other forms of hypertension.
C. This definition describes secondary hypertension, not primary hypertension. Secondary hypertension results from an identifiable underlying condition, such as kidney disease or hormonal disorders.
D. Primary hypertension can vary in severity, but it is not exclusively severe or life-threatening. While uncontrolled hypertension can lead to serious complications, primary hypertension itself does not automatically imply a critical state.
Correct Answer is B
Explanation
A. Ondansetron is not indicated for treating diarrhea. While nausea can accompany diarrhea, ondansetron specifically targets nausea and vomiting rather than the underlying causes of diarrhea.
B. Ondansetron is primarily used to prevent and treat nausea and vomiting, particularly those associated with chemotherapy, radiation therapy, and postoperative recovery. If a patient is experiencing nausea and vomiting, ondansetron would be the appropriate medication to administer.
C. Ondansetron is not indicated for managing pain. Incisional pain is typically treated with analgesics, not antiemetics. While postoperative patients may experience nausea, ondansetron would not be used solely for pain relief.
D. Paralytic ileus is a condition characterized by the lack of movement in the intestines, leading to a blockage. While nausea and vomiting can occur in this condition, ondansetron is not a treatment for the underlying issue of ileus. The focus would be on managing the ileus and any complications that arise.
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