Which inflammatory mediators cause the clinical manifestations of asthma?
Macrophages, monocytes, bradykinin.
B lymphocytes, serotonin, immunoglobulin D.
Histamine, leukotrienes, prostaglandins.
Helper T lymphocytes, natural killer cells, interleukin-1.
The Correct Answer is C
Choice A reason: Macrophages, monocytes, and bradykinin are involved in the inflammatory response, but they do not directly cause the symptoms of asthma. They may activate other cells and mediators that contribute to bronchoconstriction and mucus production.
Choice B reason: B lymphocytes, serotonin, and immunoglobulin D are not major players in the pathophysiology of asthma. B lymphocytes produce immunoglobulins, but immunoglobulin E (IgE) is the main antibody involved in allergic asthma. Serotonin is a neurotransmitter that may affect mood and sleep, but it does not cause bronchospasm. Immunoglobulin D is a rare antibody that has no known role in asthma.
Choice C reason: Histamine, leukotrienes, and prostaglandins are the main inflammatory mediators that cause the clinical manifestations of asthma. They are released by mast cells and other cells in response to allergens or irritants. They cause bronchial smooth muscle contraction, increased vascular permeability, edema, mucus secretion, and airway inflammation.
Choice D reason: Helper T lymphocytes, natural killer cells, and interleukin-1 are involved in the immune response, but they do not directly cause the symptoms of asthma. They may modulate the activation and differentiation of other cells and mediators that contribute to airway hyperresponsiveness and inflammation.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A reason: Numbness and tingling of the fingers and toes is not the expected finding because it is a sign of alkalosis, not acidosis. Alkalosis is a condition where the blood has a high pH, which means that it is too basic or alkaline. Alkalosis can cause numbness and tingling of the fingers and toes due to hypocalcemia, which is a low level of calcium in the blood, or hypokalemia, which is a low level of potassium in the blood. Both conditions can affect the nerve and muscle function, causing paresthesia, which is an abnormal sensation of the skin.
Choice B reason: A diffuse headache described as "throbbing" is the expected finding because it is a sign of acidosis, which is a condition where the blood has a low pH, which means that it is too acidic. Acidosis can cause a diffuse headache described as "throbbing" due to vasodilation, which is the widening of the blood vessels, especially in the brain. Vasodilation can increase the blood flow and the pressure in the head, causing pain and discomfort.
Choice C reason: Flushed skin that is warm to the touch is not the expected finding because it is a sign of fever, not salicylate toxicity. Fever is a condition where the body temperature is higher than normal, usually due to an infection or inflammation. Fever can cause flushed skin that is warm to the touch due to increased blood flow to the skin, which helps to dissipate the excess heat.
Choice D reason: Decreased muscle strength and deep tendon reflexes is not the expected finding because it is a sign of neuromuscular blockade, not salicylate toxicity. Neuromuscular blockade is a condition where the communication between the nerves and the muscles is impaired, causing paralysis or weakness. Neuromuscular blockade can be caused by various factors, such as medications, toxins, or diseases, that interfere with the transmission of acetylcholine, which is a neurotransmitter that stimulates the muscle contraction.
Correct Answer is B
Explanation
Choice A reason: Decreased skin turgor is not the most common clinical manifestation of nephrotic syndrome because it is a sign of dehydration, not nephrotic syndrome. Dehydration is a condition where the body loses more fluid than it takes in, which can cause the skin to lose its elasticity and firmness. Dehydration can be caused by various factors, such as vomiting, diarrhea, fever, or excessive sweating.
Choice B reason: Hypoalbuminemia is the most common clinical manifestation of nephrotic syndrome because it is a condition where the blood has a low level of albumin, which is a protein that helps maintain the fluid balance in the body. Nephrotic syndrome is a kidney disorder that causes the kidneys to leak large amounts of protein into the urine, which reduces the amount of protein in the blood. Albumin is the most abundant protein in the blood, and it helps to keep the fluid in the blood vessels, preventing it from leaking into the tissues. When the albumin level is low, the fluid can escape from the blood vessels and cause edema, which is swelling of the body parts.
Choice C reason: Decreased serum cholesterol is not the most common clinical manifestation of nephrotic syndrome because it is a condition where the blood has a low level of cholesterol, which is a type of fat that is needed for the synthesis of hormones, bile acids, and cell membranes. Decreased serum cholesterol is not a common finding in nephrotic syndrome, because the liver tends to produce more cholesterol to compensate for the loss of protein in the urine. This can lead to hypercholesterolemia, which is a condition where the blood has a high level of cholesterol, which can increase the risk of cardiovascular diseases.
Choice D reason: Increased serum sodium is not the most common clinical manifestation of nephrotic syndrome because it is a condition where the blood has a high level of sodium, which is an electrolyte that helps regulate the fluid and acid-base balance in the body. Increased serum sodium is not a common finding in nephrotic syndrome, because the kidneys tend to excrete more sodium in the urine to balance the fluid loss caused by hypoalbuminemia. This can lead to hyponatremia, which is a condition where the blood has a low level of sodium, which can cause symptoms such as confusion, weakness, seizures, and coma.
Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.
Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today