Which inflammatory mediators cause the clinical manifestations of asthma?

Macrophages, monocytes, bradykinin.

B lymphocytes, serotonin, immunoglobulin D.

Histamine, leukotrienes, prostaglandins.

Helper T lymphocytes, natural killer cells, interleukin-1.

Answer and Explanation

The Correct Answer is C

Choice A reason: Macrophages, monocytes, and bradykinin are involved in the inflammatory response, but they do not directly cause the symptoms of asthma. They may activate other cells and mediators that contribute to bronchoconstriction and mucus production.

Choice B reason: B lymphocytes, serotonin, and immunoglobulin D are not major players in the pathophysiology of asthma. B lymphocytes produce immunoglobulins, but immunoglobulin E (IgE) is the main antibody involved in allergic asthma. Serotonin is a neurotransmitter that may affect mood and sleep, but it does not cause bronchospasm. Immunoglobulin D is a rare antibody that has no known role in asthma.

Choice C reason: Histamine, leukotrienes, and prostaglandins are the main inflammatory mediators that cause the clinical manifestations of asthma. They are released by mast cells and other cells in response to allergens or irritants. They cause bronchial smooth muscle contraction, increased vascular permeability, edema, mucus secretion, and airway inflammation.

Choice D reason: Helper T lymphocytes, natural killer cells, and interleukin-1 are involved in the immune response, but they do not directly cause the symptoms of asthma. They may modulate the activation and differentiation of other cells and mediators that contribute to airway hyperresponsiveness and inflammation.

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Correct Answer is A

Explanation

Choice A reason: Infected macrophages and lymphocytes surround the Mycobacterium tuberculosis bacteria and form a tuberculous granuloma is the best explanation for the primary immune response to tuberculosis infection. A granuloma is a collection of immune cells that wall off the bacteria and prevent their spread. It is a protective mechanism that limits the infection and preserves the lung function.

Choice B reason: Tumor necrosis factor is released by T lymphocytes and lyses the Mycobacterium tuberculosis bacteria in the alveoli is not a correct explanation for the primary immune response to tuberculosis infection. Tumor necrosis factor is a cytokine that activates macrophages and induces inflammation, but it does not directly kill the bacteria. It may also have harmful effects by causing tissue damage and weight loss.

Choice C reason: Natural killer cells and neutrophils form a thick purulent debris, which becomes a caseous necrosis is not a correct explanation for the primary immune response to tuberculosis infection. Natural killer cells and neutrophils are part of the innate immune system, which is not very effective against intracellular bacteria like Mycobacterium tuberculosis. Caseous necrosis is a type of tissue death that results from the liquefaction of the granuloma. It is a sign of progressive disease, not primary infection.

Choice D reason: The inflammatory response of cytokines activates the complement system and causes permanent lung tissue damage is not a correct explanation for the primary immune response to tuberculosis infection. The inflammatory response of cytokines and the complement system are part of the innate immune system, which is not very effective against intracellular bacteria like Mycobacterium tuberculosis. Permanent lung tissue damage is a complication of chronic or reactivated tuberculosis, not primary infection.

A. Liver failure B. Diabetes mellitus C. Mercury toxicity D. Vitamin B12 deficiency

Correct Answer is B

Explanation

Choice A reason: Liver failure is not the most common cause of this type of pain because it is a condition where the liver loses its ability to perform its vital functions, such as detoxifying the blood, producing bile, and metabolizing nutrients. Liver failure can cause symptoms such as jaundice, ascites, or bleeding, but it does not usually cause burning pain in the feet.

Choice B reason: Diabetes mellitus is the most common cause of this type of pain because it is a condition where the blood glucose level is too high, either due to insufficient insulin production or reduced insulin sensitivity. Diabetes mellitus can cause damage to the nerves, especially in the peripheral areas, such as the feet, which is called diabetic neuropathy. Diabetic neuropathy can cause symptoms such as burning pain, numbness, or tingling in the feet, which can worsen at night or with pressure.

Choice C reason: Mercury toxicity is not the most common cause of this type of pain because it is a condition where the body is exposed to high levels of mercury, which is a toxic metal that can be found in some fish, dental fillings, or thermometers. Mercury toxicity can cause damage to the nervous system, causing symptoms such as tremors, memory loss, or mood changes, but it does not usually cause burning pain in the feet.

Choice D reason: Vitamin B12 deficiency is not the most common cause of this type of pain because it is a condition where the body does not have enough vitamin B12, which is a nutrient that is essential for the production of red blood cells and the maintenance of the nervous system. Vitamin B12 deficiency can cause symptoms such as anemia, fatigue, or weakness, but it does not usually cause burning pain in the feet.

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Which inflammatory mediators cause the clinical manifestations of asthma?

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Naxlex Comprehensive Predictor Exams

The nurse cares for the client with a history of pulmonary tuberculosis (TB). Two granulomas were present in the chest x-ray. Which explanation does the nurse understand best describes the primary immune response to tuberculosis infection?

Correct Answer is A

Explanation

The nurse provides care for a client who reports burning pain, which is worse at night, in both feet. The client states the pressure of the sheets on the feet is "unbearable". Which reason is the most common cause of this type of pain?

Correct Answer is B

Explanation

During assessment of a client diagnosed with severe anemia, the nurse notes pallor of the skin and mucous membranes. Which explanation is the best rationale for this finding?

A client has an acute adrenal (addisonian) crisis. Which observation is the most significant during the nursing assessment?

The nurse cares for a client who has had a left-sided intracerebral hemorrhage. The client is unable to detect light and pain touch on the right arm. Which explanation best describes these observations?

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The nurse provides care for a client immediately after a motor vehicle accident. The nurse notes BP 90/52 mmHg, absent breath sounds over the right lung, shallow RR 28 breaths/minute, and displacement of the trachea to the left side. Which explanation is correct for these findings?

The nurse provides care for a client with a hemoglobin of 8 g/dL (80 g/L) due to acute blood loss. Which finding does the nurse expect to assess?

Which risk factor is significant for the development of prerenal acute kidney injury?

The nurse provides care for a client diagnosed with pulmonary emphysema. The nurse observes the following: respiratory rate 20 breaths/minute, use of intercostal muscles, and decreased mental alertness. Which is the best explanation for these observations?