Which laboratory test result will the nurse monitor to evaluate the effects of therapy for a patient who has acute pancreatitis?

Choice A reason: Hepatic encephalopathy is a severe complication of cirrhosis caused by elevated serum ammonia levels. When the liver is unable to effectively remove ammonia from the blood due to cirrhosis, ammonia accumulates and crosses the blood-brain barrier, leading to neurological symptoms such as confusion, altered mental status, and even coma. This condition is directly related to the liver's impaired ability to detoxify the blood, making it the most consistent complication associated with elevated serum ammonia levels.
Choice B reason: Jaundice is a common symptom of cirrhosis, but it is not directly caused by elevated serum ammonia levels. Jaundice occurs due to the liver's inability to process bilirubin, a byproduct of red blood cell breakdown, leading to its accumulation in the blood and tissues. While jaundice is a sign of liver dysfunction, it is not specifically linked to ammonia levels.
Choice C reason: Ascites is the accumulation of fluid in the abdominal cavity and is a common complication of cirrhosis. It occurs due to portal hypertension and hypoalbuminemia, which result from liver dysfunction. Although ascites is a significant complication, it is not directly caused by elevated serum ammonia levels.
Choice D reason: Peripheral neuropathies are nerve damage that can occur in various conditions, but they are not typically associated with elevated serum ammonia levels in cirrhosis. Peripheral neuropathies can result from nutritional deficiencies, metabolic disorders, or other underlying conditions, but they are not a direct consequence of ammonia accumulation.

Choice A reason: Sedatives and opioids are known to cause delirium, especially in older adults or those with compromised health. These medications can affect the central nervous system, leading to confusion and cognitive impairment.
Choice B reason: Alcohol use, particularly in combination with withdrawal, can lead to delirium. Alcohol affects neurotransmitter function and can cause significant changes in mental status when consumed in excess or withdrawn abruptly.
Choice C reason: Untreated pain can contribute to delirium, particularly in patients who are already vulnerable due to age or underlying health conditions. Pain can cause significant stress on the body and mind, leading to confusion and cognitive dysfunction.
Choice D reason: Sleep deprivation is a significant factor in the development of delirium. Lack of sleep can impair cognitive function and increase the risk of delirium, especially in hospitalized patients or those with pre-existing cognitive impairments.
Choice E reason: Sensory overload, such as exposure to loud noises, bright lights, or unfamiliar environments, can contribute to delirium. Patients with sensory impairments or those in unfamiliar settings are particularly at risk.