Which medication is most likely to increase urine flow?
Furosemide
Spironolactone
Hydrochlorothiazide
Mannitol
The Correct Answer is A
Choice A reason: Furosemide, a loop diuretic, inhibits the sodium-potassium-chloride cotransporter in the thick ascending limb of the loop of Henle, preventing sodium and water reabsorption. This increases urine output significantly, often within minutes, making it highly effective for conditions like edema or heart failure, producing a rapid diuresis of up to 20% of filtered sodium.
Choice B reason: Spironolactone, a potassium-sparing diuretic, inhibits aldosterone in the distal tubule, reducing sodium reabsorption and increasing urine output. However, its diuretic effect is weaker than furosemide, as it affects only 2-3% of filtered sodium. It is primarily used for managing hyperaldosteronism or potassium retention, not rapid urine flow increase.
Choice C reason: Hydrochlorothiazide, a thiazide diuretic, inhibits sodium-chloride reabsorption in the distal convoluted tubule, increasing urine output. Its effect is milder than furosemide, impacting about 5-10% of filtered sodium. It is commonly used for hypertension but is less potent for rapid diuresis in conditions requiring significant urine flow.
Choice D reason: Mannitol, an osmotic diuretic, increases urine flow by preventing water reabsorption in the proximal tubule and loop of Henle. It is effective in acute settings like cerebral edema but less commonly used for routine diuresis compared to furosemide, which has a broader and more rapid effect on urine output.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason: An ileal conduit is typically a permanent procedure for bladder cancer after cystectomy, as the bladder is removed. Reversibility is rare and depends on specific circumstances, not guaranteed. This statement is inaccurate, as it falsely suggests that ileal conduits are always temporary and reversible.
Choice B reason: Diverting urine to the sigmoid colon describes a ureterosigmoidostomy, not an ileal conduit. In an ileal conduit, urine is diverted through an ileal segment to an abdominal stoma, not the rectum. This statement is inaccurate, as it describes a different urinary diversion procedure.
Choice C reason: An ileal conduit involves diverting urine from the ureters through a segment of ileum to a stoma on the abdomen, where urine is collected in an external pouch. This is the standard procedure for bladder cancer post-cystectomy, making this statement accurate and descriptive of the ileal conduit.
Choice D reason: An ileal conduit does not create an opening in the bladder; the bladder is often removed in bladder cancer. Urine is diverted from the ureters to a stoma, bypassing the bladder. This statement is inaccurate, as it misrepresents the anatomical changes in an ileal conduit.
Correct Answer is C
Explanation
Choice A reason: Negative glucose in urine is normal, as the kidneys reabsorb glucose unless blood levels exceed 180 mg/dL (e.g., in diabetes). In hypertension, this finding does not indicate renal damage or require further assessment, as it aligns with normal renal function and glucose handling.
Choice B reason: Negative white blood cells in urine suggest no urinary tract infection or inflammation, a normal finding. In hypertensive patients, this does not signal kidney damage or other complications, so no additional assessment is needed, as it indicates an absence of acute inflammatory processes.
Choice C reason: Proteinuria (positive protein) indicates potential renal damage, common in hypertension due to glomerular injury from elevated pressure. It suggests impaired filtration, allowing proteins like albumin to leak into urine. This finding warrants further assessment, such as quantifying protein levels or evaluating kidney function, making it the correct choice.
Choice D reason: Creatinine in urine is normal, as it is a waste product excreted by the kidneys. While serum creatinine assesses renal function, urinary creatinine presence is expected and does not indicate pathology in hypertension, so it does not require additional assessment in this context.
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