Which statement about Crohn’s disease is accurate?
Crohn’s disease always spreads to the liver
There is a patchy pattern of bowel tissue involvement
There is a continuous pattern of tissue involvement
Increases the risk of strokes in some clients
The Correct Answer is B
Choice A reason: Crohn’s disease does not always spread to the liver. While it can cause liver complications like primary sclerosing cholangitis or fatty liver in some cases, this is not universal. This statement is inaccurate, as liver involvement is a complication, not a defining feature of Crohn’s disease.
Choice B reason: Crohn’s disease is characterized by a patchy, or “skip lesion,” pattern of bowel involvement, affecting any part of the gastrointestinal tract discontinuously. Inflammation is transmural, causing fistulas or strictures. This statement is accurate, as the patchy distribution is a hallmark distinguishing it from ulcerative colitis.
Choice C reason: Continuous bowel involvement is characteristic of ulcerative colitis, not Crohn’s disease. Crohn’s affects the bowel in a segmental, patchy manner, with healthy areas between lesions. This statement is inaccurate, as it incorrectly describes Crohn’s tissue involvement pattern, which is distinctly non-continuous.
Choice D reason: Crohn’s disease increases cardiovascular risk due to chronic inflammation, but stroke is not a well-established direct complication. Inflammatory markers may contribute to atherosclerosis, but stroke risk is less specific than patchy bowel involvement. This statement is inaccurate, as it overstates a specific stroke association.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A reason: PPIs are used for short-term treatment of ulcers and gastroesophageal reflux disease (GERD), typically 4-8 weeks, not long-term, due to risks like nutrient deficiencies or infections. Long-term use is reserved for specific conditions like Barrett’s esophagus, making this statement inaccurate for general use.
Choice B reason: While PPIs are available orally and intravenously, this is not the primary focus of patient education. Their efficacy in suppressing acid production is more critical than administration routes. This statement is less relevant, as it does not address therapeutic use or safety considerations.
Choice C reason: PPIs cause adverse effects in older adults, including increased risks of fractures, Clostridium difficile infection, and vitamin B12 deficiency due to prolonged acid suppression. This statement is inaccurate, as older clients are particularly susceptible to these risks, requiring careful monitoring during PPI therapy.
Choice D reason: PPI treatment emphasizes the lowest effective dose for the shortest duration to minimize risks like infections, fractures, or nutrient malabsorption. This approach balances acid suppression with safety, especially for ulcers or GERD, making this statement accurate and critical for patient education on safe use.
Correct Answer is A
Explanation
Choice A reason: Crush injuries release myoglobin from damaged muscles, causing rhabdomyolysis. Myoglobin precipitates in renal tubules, obstructing them and leading to acute tubular necrosis, an intra-renal acute kidney injury. This toxic effect, combined with oxidative stress, impairs filtration, making this statement accurate for the pathophysiology of renal injury.
Choice B reason: Large IV fluid volumes are used to prevent renal injury in rhabdomyolysis by diluting myoglobin and maintaining perfusion. Fluid overload may cause pulmonary edema but does not typically cause pre-renal damage, which results from hypoperfusion. This statement is inaccurate, as fluids are protective, not harmful.
Choice C reason: Pain medications like NSAIDs can be nephrotoxic, causing intra-renal damage by reducing renal blood flow or causing interstitial nephritis. However, pre-renal damage results from hypoperfusion, not direct toxicity. In crush injuries, myoglobin is the primary cause, making this statement less accurate than myoglobin-related tubular damage.
Choice D reason: Significant blood loss causes pre-renal injury by reducing renal perfusion, not post-renal damage, which involves urinary obstruction. Crush injuries primarily cause intra-renal damage via myoglobin. This statement is inaccurate, as it misattributes the mechanism and type of renal injury in this context.
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