Which of the following immune disorders is characterized by the immune system attacking and damaging its own body tissues?
Allergic rhinitis
Rheumatoid arthritis
Celiac disease
Type 1 diabetes mellitus
The Correct Answer is B
Explanation: Rheumatoid arthritis is an autoimmune disorder in which the immune system mistakenly attacks the synovium (lining of the membranes that surround the joints), causing inflammation, pain, and joint damage.
Incorrect choices:
a. Allergic rhinitis is an allergic response to airborne allergens, such as pollen or pet dander, not an autoimmune disorder.
c. Celiac disease is an autoimmune disorder triggered by the ingestion of gluten, a protein found in wheat, barley, and rye, and it primarily affects the small intestine.
d. Type 1 diabetes mellitus is an autoimmune disorder in which the immune system attacks and destroys insulin-producing beta cells in the pancreas.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Explanation: During cell-mediated immunity, T cells recognize antigens that are presented by antigen-presenting cells (APCs) such as macrophages. Macrophages engulf and process pathogens, and then they display fragments of the pathogens' antigens on their cell surface using major histocompatibility complex (MHC) molecules. T cells, specifically helper T cells, interact with these antigen-presenting macrophages and become activated to initiate immune responses.
Incorrect choices:
b. B cells present antigens to helper T cells during the humoral immune response, not during cell-mediated immunity.
c. Plasma cells are not involved in antigen presentation; they are terminally differentiated B cells that produce antibodies during the humoral immune response.
d. Memory cells are formed after the immune system encounters an antigen and are not directly involved in antigen presentation.
Correct Answer is C
Explanation
Explanation: Celiac disease is an autoimmune disorder in which the immune system attacks and damages the lining of the small intestine in response to the ingestion of gluten, a protein found in wheat, barley, and rye.
Incorrect choices:
a. Rheumatoid arthritis primarily affects the joints, not the small intestine.
b. Sjögren's syndrome primarily affects the salivary and lacrimal glands, not the small intestine.
d. Type 1 diabetes mellitus is an autoimmune disorder in which the immune system attacks and destroys insulin-producing beta cells in the pancreas, not the small intestine.
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