Which of the following statements accurately describes immunodeficiency disorders?

Explanation: The correct answer is b. Common variable immunodeficiency (CVID). CVID is a primary immunodeficiency disorder characterized by a reduced level of immunoglobulins, particularly IgA, leading to an increased susceptibility to infections.

Incorrect choices:

a. Severe combined immunodeficiency (SCID) is a more severe immunodeficiency disorder that affects multiple components of the immune system, not specifically IgA levels.

c. DiGeorge syndrome is caused by a genetic abnormality and is characterized by a defect in the development of certain organs, including the thymus and parathyroid glands. It may result in immune system abnormalities but does not primarily involve IgA deficiency.

d. Wiskott-Aldrich syndrome is a rare X-linked genetic disorder that affects platelet function and immune system regulation but is not specifically associated with IgA deficiency.

Explanation: The correct answer is b. Persistent fever and night sweats. Fever and night sweats are common clinical manifestations of immunodeficiency disorders. The immune system's inability to fight off infections can lead to recurrent fevers and night sweats as the body tries to combat pathogens.

Incorrect choices:

a. Hyperactivity and restlessness are not typical clinical manifestations of immunodeficiency disorders. These symptoms are more commonly associated with conditions affecting the central nervous system.

c. Weight gain and increased appetite are not typical clinical manifestations of immunodeficiency disorders. They may be seen in conditions like hypothyroidism or hormonal imbalances.

d. Elevated blood pressure is not a common clinical manifestation of immunodeficiency disorders. It may be seen in conditions like hypertension or cardiovascular disorders.