Which type of immunodeficiency disorder is characterized by a deficiency in immunoglobulin A (Ig
a. Selective IgM deficiency
X-linked agammaglobulinemia
Common variable immunodeficiency (CVID)
Selective IgA deficiency
The Correct Answer is D
Explanation: The correct answer is d. Selective IgA deficiency. This disorder is characterized by a lack of immunoglobulin A, which can lead to an increased susceptibility to infections, particularly in the respiratory and gastrointestinal tracts.
Incorrect choices:
a. Selective IgM deficiency is a rare immunodeficiency disorder characterized by a lack of immunoglobulin M (IgM), not IgA.
b. X-linked agammaglobulinemia is a primary immunodeficiency disorder caused by a mutation in the BTK gene, resulting in a deficiency of B cells and immunoglobulins.
c. Common variable immunodeficiency (CVID) is a heterogeneous group of disorders characterized by decreased levels of immunoglobulins, including IgA, IgG, and IgM.
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Correct Answer is D
Explanation
Explanation: The correct answer is d. Immunoglobulin replacement therapy is a common treatment option for patients with primary immunodeficiency disorders. It involves infusing patients with immunoglobulins (antibodies) to help boost their immune response and protect against infections.
Incorrect choices:
a. Allergy shots are used to desensitize the immune system to specific allergens in individuals with allergies, not to treat primary immunodeficiency disorders.
b. Immunosuppressive medications are used to suppress the immune response in conditions such as autoimmune diseases or after organ transplantation, but they are not typically used to treat primary immunodeficiency disorders.
c. Blood transfusions may be used to treat anemia or certain blood disorders, but they are not a specific treatment for primary immunodeficiency disorders.
Correct Answer is C
Explanation
Explanation: The correct answer is c. X-linked agammaglobulinemia. This disorder primarily affects males and is caused by mutations in the BTK gene, resulting in a lack of mature B cells and immunoglobulins.
Incorrect choices:
a. Selective IgA deficiency is a primary immunodeficiency disorder characterized by a deficiency of immunoglobulin A (IgA), and it can affect both males and females.
b. DiGeorge syndrome is caused by a chromosome 22 deletion and is not inherited in an X-linked recessive pattern.
d. Severe combined immunodeficiency (SCID) is a group of disorders that can be inherited in various patterns, including autosomal recessive, autosomal dominant, or X-linked recessive. SCID affects both males and females and results in a severe deficiency of T cells, B cells, and natural killer (NK) cells.
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