Which type of immunodeficiency disorder is characterized by a lack of mature B cells and an inability to produce antibodies?
DiGeorge syndrome
X-linked agammaglobulinemia
Severe combined immunodeficiency (SCID)
Acquired immunodeficiency syndrome (AIDS)
The Correct Answer is B
Explanation: The correct answer is b. X-linked agammaglobulinemia. X-linked agammaglobulinemia is a primary immunodeficiency disorder caused by a genetic mutation that leads to the absence of mature B cells, resulting in an inability to produce antibodies (immunoglobulins). As a result, individuals with this disorder are highly susceptible to infections, especially bacterial infections.
Incorrect choices:
a. DiGeorge syndrome is a primary immunodeficiency disorder characterized by abnormalities in the development of certain organs, including the thymus, leading to impaired T cell function.
c. Severe combined immunodeficiency (SCID) is a group of rare genetic disorders that affect both T cells and B cells, resulting in a severe impairment of the immune system.
d. Acquired immunodeficiency syndrome (AIDS) is a secondary immunodeficiency disorder caused by the human immunodeficiency virus (HIV) infection, which specifically targets and destroys CD4+ T cells, weakening the immune system's ability to fight infections.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Explanation: The correct answer is a. "Practice proper hand hygiene and infection prevention measures." Proper hand hygiene, including regular handwashing with soap and water, is essential for clients with immunodeficiency disorders to reduce the risk of acquiring infections. It is one of the most effective ways to prevent the transmission of pathogens.
Incorrect choices:
b. Engaging in intense physical activities is not recommended for clients with immunodeficiency disorders, as it can put additional stress on the immune system. Moderate, regular exercise is beneficial for overall health, but extreme physical activities may be harmful to the immune system.
c. There is no need for clients with immunodeficiency disorders to limit their fluid intake unless they have a medical condition that requires fluid restriction. Adequate fluid intake is essential for overall health and immune function.
d. Consuming a diet rich in raw and undercooked meat is not recommended for clients with immunodeficiency disorders, as it can increase the risk of foodborne infections. It is important for these clients to follow food safety guidelines and avoid consuming raw or undercooked meat.
Correct Answer is C
Explanation
The correct answer is c. Ataxia-telangiectasia. Ataxia-telangiectasia is a rare genetic disorder that affects the cerebellum, causing poor muscle coordination (ataxia) and small, dilated blood vessels (telangiectasias). It also leads to defective T-cell function, making affected individuals more susceptible to infections.
Incorrect choices:
a. X-linked agammaglobulinemia (XLA) is a primary immunodeficiency disorder that primarily affects B-cell function, leading to a lack of mature B cells and low levels of immunoglobulins, but does not involve defective T-cell function.
b. Selective immunoglobulin A (IgA) deficiency is characterized by a deficiency of IgA, but it does not typically lead to defective T-cell function.
d. DiGeorge syndrome is caused by a deletion on chromosome 22 and primarily affects the development of certain organs, including the thymus and parathyroid glands, resulting in T-cell deficiency. While it may lead to some B-cell abnormalities, defective T-cell function is the hallmark of this disorder.
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