Which type of leukemia can be successfully treated by chemotherapy resulting in suppression, but not complete remission?
Acute lymphoblastic leukemia (ALL).
Chronic lymphocytic leukemia (CLL).
Acute myelogenous leukemia (AML).
Hairy-cell leukemia.
The Correct Answer is B
Choice A reason: Acute lymphoblastic leukemia (ALL) is an aggressive malignancy of lymphoid cells, often achieving complete remission with intensive chemotherapy, especially in children. Suppression without remission is not typical, as ALL responds well to treatment, targeting rapidly dividing blast cells. CLL, a slower-progressing disease, better fits the description of suppression without complete cure.
Choice B reason: Chronic lymphocytic leukemia (CLL) is a low-grade malignancy of mature B-lymphocytes, often managed with chemotherapy to suppress disease progression rather than achieve complete remission. CLL’s indolent nature means it can be controlled, but residual disease persists due to slow cell turnover, aligning with the question’s description of suppression.
Choice C reason: Acute myelogenous leukemia (AML) is an aggressive malignancy of myeloid cells, requiring intensive chemotherapy or stem cell transplant for potential remission. Suppression without remission is less common, as AML treatment aims for complete response. CLL’s chronic nature makes it more likely to result in disease control rather than cure.
Choice D reason: Hairy-cell leukemia is a rare, indolent B-cell malignancy highly responsive to purine analogs, often achieving long-term remission or near-cure. Suppression without remission is not characteristic, as treatment typically yields durable responses. CLL’s partial response to chemotherapy better matches the scenario of ongoing disease suppression.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason: VLDL transports triglycerides to tissues but does not reduce atherosclerosis risk. Elevated VLDL contributes to plaque formation by increasing lipid deposition in arteries. HDL’s cholesterol-removing function is protective, making VLDL incorrect, as it lacks the anti-atherogenic properties associated with decreased cardiovascular disease risk.
Choice B reason: LDL, or “bad cholesterol,” promotes atherosclerosis by depositing cholesterol in arterial walls, forming plaques. High LDL levels increase cardiovascular risk, unlike HDL, which removes cholesterol. LDL is a primary driver of atherosclerosis, making it incorrect for a lipoprotein that decreases the risk of this condition.
Choice C reason: HDL, or “good cholesterol,” reduces atherosclerosis risk by transporting cholesterol from arteries to the liver for excretion, a process called reverse cholesterol transport. High HDL levels are protective, decreasing plaque formation. This aligns with evidence-based lipid management, making HDL the correct choice for lowering cardiovascular risk.
Choice D reason: IDL, a transitional lipoprotein between VLDL and LDL, contributes to atherosclerosis by delivering cholesterol to arteries. Unlike HDL, IDL does not have protective, cholesterol-removing properties. IDL’s role in lipid metabolism increases cardiovascular risk, making it incorrect for reducing atherosclerosis risk.
Correct Answer is A
Explanation
Choice A reason: In hypothyroidism, elevated TSH reflects the pituitary’s attempt to stimulate an underactive thyroid, often causing goiter due to glandular hypertrophy. TSH rises to compensate for low thyroid hormone production, leading to thyroid enlargement. This aligns with the pathophysiology of goiter in primary hypothyroidism, supporting the clinical finding.
Choice B reason: Iodine levels are not routinely measured in hypothyroidism and do not directly cause goiter. Iodine deficiency may contribute to goiter but is less common in developed regions. Elevated TSH, not iodine, drives thyroid enlargement in hypothyroidism, making this an incorrect marker for supporting the goiter finding.
Choice C reason: Calcium levels are unrelated to goiter or hypothyroidism unless parathyroid dysfunction is involved. Goiter results from TSH-driven thyroid hypertrophy due to low thyroid hormones. Calcium does not influence thyroid enlargement, making it an irrelevant laboratory result for supporting the client’s goiter in this context.
Choice D reason: Serum T3 and T4 are decreased in hypothyroidism, not increased, as the thyroid fails to produce adequate hormones. Low T3/T4 triggers high TSH, causing goiter. Increased T3/T4 would suggest hyperthyroidism, not hypothyroidism with goiter, making this an incorrect choice for supporting the clinical finding.
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