A 45-year-old patient presents to the emergency department with epigastric pain, nausea, and occasional vomiting. The patient's history reveals chronic NSAID use for osteoarthritis. Laboratory tests indicate normal liver function but show the presence of Helicobacter pylori antibodies. Which of the following is the most likely diagnosis?
Peptic ulcer disease
Acute gastritis due to NSAID use
Functional dyspepsia
Chronic gastritis due to Helicobacter pylori infection
The Correct Answer is D
A. Peptic ulcer disease is possible, but the patient's NSAID use and positive H. pylori antibodies suggest a more specific cause related to gastritis.
B. Acute gastritis due to NSAID use is likely since NSAIDs can irritate the stomach lining and increase the risk of ulcers.
C. Functional dyspepsia is less likely given the presence of H. pylori antibodies, which typically indicate an active infection.
D. Chronic gastritis due to Helicobacter pylori infection is the most likely diagnosis, especially with the combination of NSAID use and positive H. pylori antibodies.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["C","E","F"]
Explanation
A. A diet rich in fruits and vegetables is generally protective against colorectal cancer due to the high fiber content and antioxidants, reducing cancer risk.
B. Moderate alcohol consumption can increase the risk of colorectal cancer, as alcohol has been linked to inflammation and changes in gut microbiota, which may contribute to carcinogenesis.
C. A diet high in red and processed meats has been strongly associated with an increased risk of colorectal cancer due to the presence of carcinogenic substances like nitrates and heterocyclic amines in processed meats.
D. A low body mass index (BMI) is actually protective against cancer in general, as obesity is a significant risk factor for colorectal cancer due to its association with increased inflammation and insulin resistance.
E. Genetic factors such as having a family history of colorectal cancer increase the risk significantly. Inherited syndromes like familial adenomatous polyposis or Lynch syndrome increase the likelihood of developing this cancer.
F. Chronic inflammatory bowel diseases such as Crohn's disease or ulcerative colitis increase the risk of colorectal cancer due to the prolonged inflammation and cellular damage they cause in the colon.
G. Regular physical activity has a protective effect against colorectal cancer by reducing inflammation, improving immune function, and regulating bowel movement.
Correct Answer is B
Explanation
A. A glass of wine per day can worsen GERD symptoms, as alcohol can relax the lower esophageal sphincter and increase reflux.
B. Practicing good oral hygiene is essential in preventing dental erosion and other complications associated with GERD, as stomach acid can damage teeth and gums.
C. Laying down after eating increases the risk of acid reflux, which can worsen GERD symptoms.
D. Citrus foods are acidic and can trigger GERD symptoms, so increasing their intake is not recommended.
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