A client has been diagnosed with cancer.
The physician prescribes antineoplastic drug therapy to the client.
Which of the following would the nurse include in the discussion about the prescribed therapy?

Choice A rationale:

Aminoglycosides are known to have nephrotoxic effects. Nephrotoxicity refers to kidney toxicity, and aminoglycosides can cause damage to the renal tubules, leading to impaired kidney function. The nurse should be alert to this potential toxicity when administering these drugs, as it can result in kidney dysfunction, altered serum creatinine levels, and electrolyte imbalances.

Choice B rationale:

Cardiotoxicity is not typically associated with aminoglycosides. These antibiotics primarily affect the kidneys and the inner ear. There is no direct relationship between aminoglycosides and cardiac toxicity.

Choice C rationale:

Hepatotoxicity refers to liver toxicity and is not a common side effect of aminoglycosides. Aminoglycosides are primarily metabolized in the kidneys and are excreted through urine, making kidney toxicity a more significant concern.

Choice D rationale:

Cytotoxicity is a broad term that refers to the toxicity of cells. Aminoglycosides do not typically cause generalized cytotoxic effects in the body. Their primary toxicities are related to specific organ systems, such as the kidneys and the inner ear.