A client with HIV infection asks the nurse about the different classes of antiretroviral drugs used for treatment. Which of the following statements by the client indicates a need for further education?
"Integrase strand transfer inhibitors (INSTIs) block the enzyme integrase that inserts HIV DNA into the host cell genome.”
"Non-nucleoside reverse transcriptase inhibitors (NNRTIs) block the entry of HIV into the host cell by interfering with the binding of the virus to the cell surface receptors or co-receptors.”
"Protease inhibitors (PIs) block the enzyme protease that cleaves HIV proteins into functional units.”
"Nucleoside reverse transcriptase inhibitors (NRTIs) block the enzyme reverse transcriptase that converts HIV RNA into DNA.”
The Correct Answer is B
Choice A rationale:
The client's statement about Integrase strand transfer inhibitors (INSTIs) is accurate. INSTIs block the enzyme integrase, preventing the insertion of HIV DNA into the host cell genome.
Choice B rationale:
This is the correct answer. The client's statement about Non-nucleoside reverse transcriptase inhibitors (NNRTIs) is incorrect. NNRTIs work by directly binding to reverse transcriptase, blocking its activity, and preventing HIV replication.
Choice C rationale:
The client's statement about Protease inhibitors (PIs) is accurate. PIs block the enzyme protease, inhibiting the cleavage of HIV proteins and preventing the formation of mature viral particles.
Choice D rationale:
The client's statement about Nucleoside reverse transcriptase inhibitors (NRTIs) is accurate. NRTIs are incorporated into the growing viral DNA chain, leading to chain termination and preventing further viral replication.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice C rationale:
"Using condoms consistently and correctly during sexual intercourse can reduce the risk of HIV transmission." This statement is accurate and supported by scientific evidence. Condoms act as a barrier method and are effective in preventing the exchange of bodily fluids, thus reducing the likelihood of HIV transmission during sexual activity.
Choice A rationale:
"You should avoid getting tested for HIV regularly." This statement is incorrect and potentially harmful. Regular HIV testing is essential for early detection and timely initiation of treatment if needed. Early diagnosis improves health outcomes and reduces the risk of transmitting the virus to others.
Choice B rationale:
"Pre-exposure prophylaxis (PrEP) is used after HIV exposure." This statement is incorrect. PrEP is taken before potential HIV exposure to prevent infection. It involves taking antiretroviral medications regularly to reduce the risk of acquiring the virus.
Choice D rationale:
"Supervised injection facilities aim to increase risky behaviors among drug users." This statement is incorrect. Supervised injection facilities provide a safe and controlled environment for drug users to consume drugs under medical supervision, reducing the risk of overdose and the transmission of infectious diseases like HIV and hepatitis
C.
Correct Answer is C
Explanation
Choice A rationale:
The acute primary infection is the initial phase of HIV infection and occurs shortly after exposure. During this stage, the viral load may be high, but the CD4 count is usually not significantly affected yet.
Choice B rationale:
The asymptomatic stage follows the acute primary infection and is characterized by no symptoms or mild symptoms. The viral load and CD4 count may be stable or slowly changing during this stage.
Choice C rationale:
The symptomatic stage is the next phase of HIV infection, also known as the early symptomatic or clinical latency stage. During this stage, the viral load is often associated with a high viral load and a low CD4 count. The immune system is weakened, and the individual may experience various HIV-related symptoms.
Choice D rationale:
AIDS is the final stage of HIV infection. At this stage, the immune system is severely compromised, and the individual is susceptible to various opportunistic infections and certain cancers. While the viral load remains high, the CD4 count is significantly low.
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