A client with nephrotic syndrome is experiencing hyperlipidemia. What is the rationale for elevated lipid levels in this client?

Increased cholesterol synthesis in the liver.

Impaired fat absorption in the small intestine.

Reduced clearance of lipids by the kidneys.

Elevated blood glucose levels and insulin resistance.

Answer and Explanation

The Correct Answer is C

A. Incorrect. While increased cholesterol synthesis in the liver can contribute to hyperlipidemia, it is not the primary reason for elevated lipid levels in nephrotic syndrome.

B. Incorrect. Impaired fat absorption in the small intestine is not a significant factor contributing to hyperlipidemia in nephrotic syndrome.

C. Correct. Nephrotic syndrome results in increased protein loss, including proteins involved in lipid transport and metabolism. Reduced clearance of lipids by the kidneys leads to elevated lipid levels in the bloodstream.

D. Incorrect. Elevated blood glucose levels and insulin resistance are not directly related to hyperlipidemia in nephrotic syndrome.

QUESTIONS

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Correct Answer is D

Explanation

A. Incorrect. Elevated platelet count and clotting factors are not characteristic of nephrotic syndrome. Clients with nephrotic syndrome tend to have normal platelet counts.

B. Incorrect. Decreased blood viscosity and enhanced blood flow would not directly lead to an increased risk of thromboembolic events in nephrotic syndrome.

C. Incorrect. While impaired liver function may impact clotting factors, it is not a common manifestation of nephrotic syndrome.

D. Correct. Nephrotic syndrome is associated with a loss of anticoagulant proteins, particularly antithrombin III, in the urine. This loss of anticoagulant proteins contributes to a state of hypercoagulability, increasing the risk of thromboembolic events, such as deep vein thrombosis and pulmonary embolism.

A. To prevent clot formation in the urinary tract due to increased proteinuria. B. To reduce inflammation and pain associated with kidney damage. C. To decrease the risk of infection related to hypoalbuminemia. D. To prevent blood clot formation in the glomerular capillaries.

Correct Answer is D

Explanation

A. Incorrect. While increased proteinuria can increase the risk of clot formation in the urinary tract, anticoagulant therapy is not typically prescribed for this reason in nephrotic syndrome.

B. Incorrect. Anticoagulants are not primarily used to reduce inflammation and pain associated with kidney damage.

C. Incorrect. Anticoagulants do not directly impact the risk of infection related to hypoalbuminemia.

D. Correct. Nephrotic syndrome can cause damage to the glomerular capillaries, leading to clot formation. Anticoagulant therapy is prescribed to prevent clot formation in the kidneys and reduce the risk of complications such as renal vein thrombosis.

QUESTIONS

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A client with nephrotic syndrome is experiencing hyperlipidemia. What is the rationale for elevated lipid levels in this client?

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Naxlex Comprehensive Predictor Exams

A client with nephrotic syndrome is at increased risk of developing thromboembolic events. What is the underlying pathophysiological reason for this increased risk?

Correct Answer is D

Explanation

A client with nephrotic syndrome is prescribed anticoagulant therapy. What is the rationale for administering anticoagulants in nephrotic syndrome?

Correct Answer is D

Explanation

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