A client with Paget's disease complains of bone pain that worsens with activity. What is the underlying cause of this pain?
Decreased blood flow to bones
Bone infarction
Microfractures and inflammation
Compression of nerve roots
The Correct Answer is C
The bone pain experienced by clients with Paget's disease is often due to microfractures and inflammation in the affected bones. The increased bone turnover and remodeling lead to weaker bones, making them more susceptible to microfractures. The inflammation at the site of these microfractures contributes to the pain, which worsens with activity.
a. Decreased blood flow to bones: Paget's disease does not typically cause decreased blood flow to bones. Instead, the condition leads to increased vascularity in affected bones.
b. Bone infarction: Bone infarction (death of bone tissue due to inadequate blood supply) is not a characteristic feature of Paget's disease. Microfractures and inflammation are more common causes of bone pain in this condition.
d. Compression of nerve roots: While nerve compression can cause bone pain, it is not a primary mechanism of pain in Paget's disease. The pain is primarily related to bone remodeling and inflammation.
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Related Questions
Correct Answer is B
Explanation
Monitoring serum calcium levels is important during bisphosphonate therapy for Paget's disease. Bisphosphonates can affect calcium metabolism, and monitoring calcium levels helps ensure appropriate dosing and prevent complications such as hypocalcemia or hypercalcemia.
a. Liver function tests (LFTs): Bisphosphonates generally do not have a significant impact on liver function. Monitoring LFTs is not a primary concern during bisphosphonate therapy.
c. Blood glucose levels: Bisphosphonate therapy is not known to affect blood glucose levels. Monitoring blood glucose is not directly related to Paget's disease treatment.
d. Complete blood count (CBC): Bisphosphonate therapy does not typically have a major effect on blood cell counts. Monitoring a CBC is not a primary concern during bisphosphonate treatment for Paget's disease.
Correct Answer is C
Explanation
The main difference between Paget's disease and osteoporosis is in the underlying bone remodeling. Paget's disease is characterized by increased bone turnover and disordered bone formation, while osteoporosis involves decreased bone formation and increased bone resorption.
a. Paget's disease is characterized by decreased bone density, while osteoporosis is associated with increased bone density: This statement is incorrect. In Paget's disease, bone density can be normal or increased due to the disordered bone remodeling.
b. Paget's disease primarily affects trabecular bone, while osteoporosis affects cortical bone: This statement is incorrect. Both Paget's disease and osteoporosis can affect both trabecular and cortical bone.
d. Paget's disease is an autoimmune disorder, while osteoporosis is caused by hormonal imbalances: This statement is incorrect. Paget's disease is not an autoimmune disorder, and osteoporosis is not solely caused by hormonal imbalances. Both conditions have complex multifactorial etiologies.
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