The nurse is providing patient education to a client with Paget's disease. Which statement by the client indicates an understanding of the condition?
"Paget's disease is a type of cancer that affects the bones."
"This condition is caused by a deficiency in vitamin D."
"I should avoid weight-bearing exercises to prevent fractures."
"I will take my prescribed bisphosphonate medication with a full glass of milk."
The Correct Answer is D
Bisphosphonate medications are commonly prescribed for Paget's disease to slow down bone resorption and promote more balanced bone remodeling. Taking bisphosphonates with a full glass of water or milk helps ensure proper absorption and reduce the risk of gastrointestinal irritation.
a. "Paget's disease is a type of cancer that affects the bones." This statement is incorrect. Paget's disease is not a type of cancer but a chronic, non-cancerous condition characterized by abnormal bone remodeling.
b. "This condition is caused by a deficiency in vitamin D." This statement is incorrect. While vitamin D plays a role in bone health, Paget's disease is primarily a result of genetic factors that lead to abnormal bone remodeling.
c. "I should avoid weight-bearing exercises to prevent fractures." This statement is incorrect. Moderate weight-bearing exercises, under healthcare provider guidance, can help maintain bone strength and reduce the risk of fractures in individuals with Paget's disease.
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Correct Answer is B
Explanation
The goal of treatment for Paget's disease is to relieve pain and prevent complications associated with bone deformities and fractures. There is no cure for Paget's disease, but treatment aims to manage symptoms and reduce the risk of complications.
a. Cure the disease completely: Paget's disease is a chronic condition with no known cure. Treatment focuses on symptom management and preventing complications.
c. Restore normal bone density: While treatment may aim to reduce abnormal bone remodeling, restoring normal bone density is not typically achievable. The focus is on pain relief and preventing complications.
d. Regenerate damaged bones: While treatment may improve bone health and reduce deformities, regenerating damaged bones to their original state is not feasible. Treatment aims to manage the disease and its consequences effectively.
Correct Answer is C
Explanation
Osteoclasts are the primary cell type responsible for bone resorption in Paget's disease. These cells become overactive, leading to excessive bone breakdown, which is a hallmark of the condition.
a. Osteocytes: Osteocytes are mature bone cells embedded in the bone matrix. While they play a role in maintaining bone health, they are not directly responsible for bone resorption.
b. Osteoblasts: Osteoblasts are bone-forming cells. In Paget's disease, they attempt to repair the resorbed bone but their activity is disordered, leading to structurally abnormal bone formation.
d. Osteoprogenitor cells: Osteoprogenitor cells are undifferentiated cells that can differentiate into osteoblasts. They are not directly involved in the increased bone resorption seen in Paget's disease.
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