A group of nursing students is reviewing information about upper gastrointestinal system drugs.
The students demonstrate understanding of the material when they identify which of the following as a proton pump inhibitor?
Nizatidine.
Omeprazole.
Sucralfate.
Misoprostol.
The Correct Answer is B
Choice A rationale:
Nizatidine is not a proton pump inhibitor; it is an H2 receptor antagonist. It works by blocking the histamine H2 receptors in the stomach, reducing acid production. Proton pump inhibitors (PPIs) work differently by directly inhibiting the proton pump (H+/K+ ATPase) responsible for acid secretion in the stomach.
Choice B rationale:
Omeprazole is a proton pump inhibitor (PPI). PPIs are drugs that reduce gastric acid production by inhibiting the proton pump (H+/K+ ATPase) in the parietal cells of the stomach. This action is highly effective in treating conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers.
Choice C rationale:
Sucralfate is not a proton pump inhibitor; it is a medication that forms a protective barrier over ulcers and erosions in the stomach and intestines. It does not directly affect acid production.
Choice D rationale:
Misoprostol is not a proton pump inhibitor; it is a synthetic prostaglandin E1 analog. It is primarily used to prevent gastric ulcers in individuals who are at high risk due to chronic nonsteroidal anti-inflammatory drug (NSAID) use. It has a protective effect on the gastric mucosa but does not inhibit acid secretion.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Correct Answer is A
Explanation
Choice A rationale:
Isoniazid Isoniazid is one of the first-line drugs used in the initial treatment phase of tuberculosis (TB). It is a key component of the standard regimen for TB treatment. Isoniazid is highly effective against Mycobacterium tuberculosis, the bacterium responsible for TB, and it plays a critical role in the initial phase of treatment to rapidly reduce the bacterial load.
Choice B rationale:
Ciprofloxacin Ciprofloxacin is not a first-line drug for the treatment of tuberculosis. While it has antibacterial properties, it is not considered one of the primary agents for TB treatment. It is more commonly used to treat other types of bacterial infections, such as urinary tract infections.
Choice C rationale:
Gentamycin Gentamycin is not typically used as a first-line treatment for TB. It is reserved for specific situations, such as drug-resistant TB cases, and is not part of the standard initial treatment regimen for TB.
Choice D rationale:
Clindamycin Clindamycin is not a first-line drug for the treatment of tuberculosis. It is primarily used to treat anaerobic bacterial infections and is not a standard part of TB treatment protocols.
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