A group of nursing students is reviewing information about upper gastrointestinal system drugs.
The students demonstrate understanding of the material when they identify which of the following as a proton pump inhibitor?
Nizatidine.
Omeprazole.
Sucralfate.
Misoprostol.
The Correct Answer is B
Choice A rationale:
Nizatidine is not a proton pump inhibitor; it is an H2 receptor antagonist. It works by blocking the histamine H2 receptors in the stomach, reducing acid production. Proton pump inhibitors (PPIs) work differently by directly inhibiting the proton pump (H+/K+ ATPase) responsible for acid secretion in the stomach.
Choice B rationale:
Omeprazole is a proton pump inhibitor (PPI). PPIs are drugs that reduce gastric acid production by inhibiting the proton pump (H+/K+ ATPase) in the parietal cells of the stomach. This action is highly effective in treating conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers.
Choice C rationale:
Sucralfate is not a proton pump inhibitor; it is a medication that forms a protective barrier over ulcers and erosions in the stomach and intestines. It does not directly affect acid production.
Choice D rationale:
Misoprostol is not a proton pump inhibitor; it is a synthetic prostaglandin E1 analog. It is primarily used to prevent gastric ulcers in individuals who are at high risk due to chronic nonsteroidal anti-inflammatory drug (NSAID) use. It has a protective effect on the gastric mucosa but does not inhibit acid secretion.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A rationale:
Nonprotease inhibitors are not typically a part of HAART (Highly Active Antiretroviral Therapy). Protease inhibitors are used to inhibit HIV replication.
Choice B rationale:
Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are often used in HAART, but they are not the primary agents responsible for inhibiting the integration of the viral genome into the host cell's DNA. NNRTIs target the reverse transcriptase enzyme.
Choice C rationale:
Entry inhibitors are another class of antiretroviral drugs, but they work by blocking the entry of the virus into host cells, not by inhibiting integration. They are used in combination with other drugs in specific cases.
Choice D rationale:
Integrase inhibitors are a class of antiretroviral drugs that specifically target the enzyme integrase, which is responsible for integrating the viral genome into the host cell's DNA. This choice is correct because integrase inhibitors are a crucial component of HAART and help prevent the virus from replicating in the host's cells.
Correct Answer is D
Explanation
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