A nurse would expect to administer antihelminthic therapy cautiously to which of the following clients?

Clients who have cardiac disease.

Clients with hepatic impairment.

Clients with diabetes.

Clients with respiratory disorders.

Answer and Explanation

The Correct Answer is B

Choice A rationale:

Antihelminthic therapy does not need to be administered cautiously in clients who have cardiac disease unless there are specific contraindications or drug interactions that would necessitate caution. The primary concern in these cases would be ensuring that the chosen antihelminthic drug does not interact adversely with the medications used to manage the client's cardiac condition.

Choice B rationale:

Antihelminthic therapy should be administered cautiously in clients with hepatic impairment. The liver plays a significant role in drug metabolism and elimination. Clients with hepatic impairment may have altered drug metabolism, which can affect the pharmacokinetics of antihelminthic drugs. Therefore, caution is needed to adjust the dosing and monitor for potential side effects in clients with compromised liver function.

Choice C rationale:

Clients with diabetes do not typically require cautious administration of antihelminthic therapy solely due to their diabetes. However, it is essential to consider potential drug interactions with antidiabetic medications that the client may be taking. The primary concern would be ensuring that the antihelminthic drug does not interfere with diabetes management.

Choice D rationale:

Clients with respiratory disorders do not necessarily require cautious administration of antihelminthic therapy based solely on their respiratory condition. However, it is crucial to consider potential drug interactions with medications used to manage the respiratory disorder. Antihelminthic drugs are primarily targeted at parasitic infections and may not directly impact respiratory conditions.

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Correct Answer is A

Explanation

Choice A rationale:

Alkylating agents are cell cycle-specific drugs. They work on cells during various stages of the cell cycle and are classified as cell cycle phase-nonspecific drugs. These drugs form covalent bonds with DNA, preventing DNA replication and transcription. This action disrupts the cell cycle, making them effective against actively dividing cells.

Choice B rationale:

Plant alkaloids are not cell cycle-specific drugs. Plant alkaloids, such as vinblastine and vincristine, are derived from plants and are classified as cell cycle phase-specific drugs. They primarily affect cells during the M phase of the cell cycle by disrupting microtubule formation. While they are effective against rapidly dividing cells, they are not cell cycle-specific.

Choice C rationale:

Antineoplastic antibiotics are not cell cycle-specific drugs. These drugs, such as doxorubicin and daunorubicin, are used in cancer treatment and primarily work by intercalating with DNA and inhibiting topoisomerase enzymes. Their mechanisms of action do not specifically target a particular phase of the cell cycle, making them cell cycle phase-nonspecific.

Choice D rationale:

Retinoids are not cell cycle-specific drugs. Retinoids are derived from vitamin A and have various mechanisms of action, including regulating cell growth and differentiation. They are not classified as cell cycle-specific drugs.

A. Digoxin (Lanoxin). B. Phenytoin (Dilantin). C. Vancomycin (Vancocin). D. Carbamazepine (Tegretol). .

Correct Answer is A

Explanation

Choice A rationale: Tetracycline can increase the levels of digoxin (Lanoxin) in the blood, leading to an increased risk of digoxin toxicity. This interaction occurs because tetracycline can interfere with the metabolism and excretion of digoxin, causing higher concentrations of the drug in the bloodstream1. Symptoms of digoxin toxicity include nausea, vomiting, dizziness, and cardiac arrhythmias. Therefore, patients taking both medications should be closely monitored for signs of toxicity and may require dosage adjustments.

Choice B rationale: Phenytoin (Dilantin) does not have a significant interaction with tetracycline that increases the risk of toxicity. While both medications can be used together, they do not significantly affect each other's metabolism or excretion1.

Choice C rationale: Vancomycin (Vancocin) does not have a significant interaction with tetracycline that increases the risk of toxicity. Both medications can be used together without causing significant changes in their metabolism or excretion1.

Choice D rationale: Carbamazepine (Tegretol) does not have a significant interaction with tetracycline that increases the risk of toxicity. While both medications can be used together, they do not significantly affect each other's metabolism or excretion

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A nurse would expect to administer antihelminthic therapy cautiously to which of the following clients?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A group of nursing students are reviewing antineoplastic drugs.The students demonstrate understanding of the information when they identify which of the following as cell cycle specific?

Correct Answer is A

Explanation

A nurse is reviewing the medical record of a client who is prescribed tetracycline. The nurse would be alert for an increased risk of toxicity if the client is taking which of the following?

Correct Answer is A

Explanation

The parents of a child who is recovering from chickenpox tell the nurse that they gave the child aspirin for his fever.The nurse would be alert to the development of which of the following?

A nurse is preparing to administer an aminoglycoside to a client.The nurse would be alert for the development of which of the following toxicities?

A nurse is teaching a patient about the common adverse reactions that can occur with his prescribed therapy with cephalosporins.The nurse determines that the teaching was successful when the patient identifies which of the following?

A client has been receiving treatment with antineoplastic drugs that depress the bone marrow.Which preadministration assessment would be most important for the nurse to complete with respect to this effect?

The nurse is teaching a client about possible adverse reactions that can occur with tetracyclines.The nurse determines that the teaching was successful when the client identifies which of the following?

A patient develops a superinfection due to fluoroquinolone therapy.The patient asks the nurse why this happened.Which response by the nurse would be most appropriate?

A nurse understands that anthelmintic drugs are contraindicated in which patients?