A nurse is caring for a client who is receiving warfarin therapy.
Which of the following medications should the nurse expect to administer if the client develops bleeding as an adverse effect of the medication? (Select all that apply.).

Choice A rationale:

Tapeworm. Tapeworm infections are caused by parasites known as cestodes. Antiprotozoal drugs are primarily used to treat infections caused by protozoa, which are a different type of pathogen. Tapeworms are not protozoa; they are classified as helminths. Therefore, using antiprotozoal drugs for tapeworm infections is not indicated.

Choice B rationale:

Aspergillosis. Aspergillosis is a fungal infection caused by Aspergillus species. Antiprotozoal drugs are not effective against fungal infections. They are designed to target protozoa, which are a different group of microorganisms. Therefore, antiprotozoal drugs are not indicated for the treatment of aspergillosis.

Choice D rationale:

Cryptococcal meningitis. Cryptococcal meningitis is a fungal infection caused by Cryptococcus neoformans. Like aspergillosis, it is caused by a fungus, not a protozoan parasite. Antiprotozoal drugs are not appropriate for the treatment of fungal infections. Therefore, the use of antiprotozoal drugs is not indicated for cryptosporidium meningitis.

Choice C rationale:

Giardiasis. Giardiasis is an intestinal infection caused by the protozoan parasite Giardia lamblia. Antiprotozoal drugs, such as metronidazole, are effective in treating giardiasis. These drugs target protozoa and disrupt their cellular functions, making them a suitable choice for the treatment of giardiasis.

Choice A rationale:

Aminoglycosides are known to have nephrotoxic effects. Nephrotoxicity refers to kidney toxicity, and aminoglycosides can cause damage to the renal tubules, leading to impaired kidney function. The nurse should be alert to this potential toxicity when administering these drugs, as it can result in kidney dysfunction, altered serum creatinine levels, and electrolyte imbalances.

Choice B rationale:

Cardiotoxicity is not typically associated with aminoglycosides. These antibiotics primarily affect the kidneys and the inner ear. There is no direct relationship between aminoglycosides and cardiac toxicity.

Choice C rationale:

Hepatotoxicity refers to liver toxicity and is not a common side effect of aminoglycosides. Aminoglycosides are primarily metabolized in the kidneys and are excreted through urine, making kidney toxicity a more significant concern.

Choice D rationale:

Cytotoxicity is a broad term that refers to the toxicity of cells. Aminoglycosides do not typically cause generalized cytotoxic effects in the body. Their primary toxicities are related to specific organ systems, such as the kidneys and the inner ear.