A nasal spray of desmopressin acetate (DDAVP) is used to treat which endocrine disorder of the pituitary gland?

Diabetes insipidus

Acute adrenocortical insufficiency

Hypopituitarism

Syndrome of inappropriate antidiuretic hormone

Answer and Explanation

The Correct Answer is A

Choice A reason:

Diabetes insipidus: Desmopressin acetate (DDAVP) is primarily used to treat central diabetes insipidus, a condition where the body lacks sufficient antidiuretic hormone (ADH) due to issues with the pituitary gland or hypothalamus. This hormone helps regulate water balance in the body, and desmopressin acts as a synthetic replacement to reduce frequent urination and excessive thirst.

Choice B Reason:

Acute adrenocortical insufficiency: This condition, also known as Addison’s disease, involves insufficient production of cortisol and aldosterone by the adrenal glands. Desmopressin is not used to treat this condition as it does not address the hormonal deficiencies involved.

Choice C Reason:

Hypopituitarism: This condition involves the underproduction of one or more hormones by the pituitary gland. While desmopressin can be used to manage specific symptoms related to ADH deficiency, it is not a comprehensive treatment for hypopituitarism, which requires hormone replacement therapy for multiple hormones.

Choice D Reason:

Syndrome of inappropriate antidiuretic hormone (SIADH): SIADH is characterized by excessive release of ADH, leading to water retention and hyponatremia. Desmopressin is not used to treat SIADH; in fact, it would exacerbate the condition by increasing ADH levels.

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Correct Answer is ["2"]

Explanation

Calculation Steps

Step 1: Determine the total urine output in mL.

Total urine output = 360 mL

Step 2: Determine the child’s weight in kg.

Weight = 15 kg

Step 3: Determine the time period in hours.

Time = 12 hours

Step 4: Calculate the urine output in mL/kg/hour.

Urine output (mL/kg/hour) = Total urine output ÷ (Weight × Time)

Step 5: Perform the multiplication inside the parentheses first.

Weight × Time = 15 kg × 12 hours = 180 kg·hours

Step 6: Perform the division.

Urine output (mL/kg/hour) = 360 mL ÷ 180 kg·hours = 2 mL/kg/hour

Result

The child’s urine output is 2 mL/kg/hour.

A. Weight loss despite increased eating B. Pale, moist skin C. Weight gain and fluid overload D. Poor sleep with frequent awakening

Correct Answer is A

Explanation

Choice A reason:

Weight loss despite increased eating is a classic symptom of type 1 diabetes mellitus in children. This occurs because the body is unable to use glucose for energy due to a lack of insulin. As a result, the body starts breaking down fat and muscle for energy, leading to weight loss even though the child may have an increased appetite.

Choice B Reason:

Pale, moist skin is not typically associated with type 1 diabetes mellitus. This symptom is more commonly related to conditions such as anemia or infections. In type 1 diabetes, the skin may actually appear dry due to dehydration caused by high blood sugar levels.

Choice C Reason:

Weight gain and fluid overload are not characteristic of type 1 diabetes mellitus. In fact, children with type 1 diabetes often experience weight loss. Fluid overload is more commonly seen in conditions such as heart failure or kidney disease.

Choice D Reason:

Poor sleep with frequent awakening is not a specific symptom of type 1 diabetes mellitus. While children with diabetes may experience nocturia (frequent urination at night) due to high blood sugar levels, this is not the primary clinical manifestation. The main symptoms are related to hyperglycemia and the body’s inability to use glucose for energy.

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A nasal spray of desmopressin acetate (DDAVP) is used to treat which endocrine disorder of the pituitary gland?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A 15 kg child has a urine output of 360 mL during the past 12 hours. Calculate the child’s urine output in mL/kg/hour for this period of time. (Do not enter units).

Correct Answer is ["2"]

Explanation

Type 1 diabetes mellitus is suspected in a child. Which clinical manifestation may be present?

Correct Answer is A

Explanation

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