A nurse is assessing a client suspected to have cholecystitis. Which of the following clinical manifestations should the nurse prioritize as a hallmark symptom of this condition?

Choice A reason:

Taking the PPI with meals is not the most effective timing for acid suppression. PPIs work best when taken on an empty stomach.

Choice B reason:

This statement is correct. PPIs are most effective when taken on an empty stomach, about 30 minutes before a meal. This allows the medication to be absorbed and inhibit acid secretion in the stomach before food intake.

Choice C reason:

While consistency in medication timing is important, taking the PPI at any time of the day may not optimize its effectiveness.

Choice D reason:

Taking the PPI before bedtime may not provide the best acid suppression throughout the day. Taking it on an empty stomach before a meal is a more appropriate approach.

Choice A reason:

This statement is correct. Right upper quadrant abdominal pain that radiates to the right shoulder is a hallmark symptom of cholecystitis. The pain is typically sudden, severe, and constant, and it is often triggered by a fatty meal.

Choice B reason:

Left lower quadrant abdominal pain with rebound tenderness is not characteristic of cholecystitis. It may indicate other conditions, such as diverticulitis or appendicitis.

Choice C reason:

Midline epigastric pain aggravated by lying down is more indicative of gastroesophageal reflux disease (GERD) rather than cholecystitis.

Choice D reason:

Diffuse abdominal pain with a low-grade fever may be seen in various conditions, but it does not specifically point to cholecystitis.