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A nurse is caring for a client who has been prescribed prochlorperazine (Compazine) for postoperative nausea. Which of the following reported signs can indicate a potential complication of this medication?

A.

Nausea

B.

Prolonged QT interval

C.

Restlessness

D.

Vomiting

Answer and Explanation

The Correct Answer is C

A. Nausea is the symptom prochlorperazine is intended to treat, so its occurrence would suggest that the medication is not effective rather than being a complication. 

B. Prolonged QT interval is not a typical complication of prochlorperazine; it is more commonly associated with medications like ondansetron. 

C. Restlessness can indicate akathisia, a potential extrapyramidal side effect of prochlorperazine. This condition involves an intense feeling of restlessness and the need to move, commonly associated with dopamine antagonists. 

D. Vomiting is a symptom treated by prochlorperazine and would likely occur due to inadequate control rather than being a complication of the drug itself. 


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Related Questions

Correct Answer is ["C","D"]

Explanation

A. Glucagon (Glucagen): Glucagon is used to treat severe hypoglycemia and is not indicated for managing EPS or involuntary muscle spasms.

B. Metformin (Glucophage): Metformin is an oral hypoglycemic agent used to manage diabetes mellitus and is not relevant for treating EPS or involuntary muscle spasms.

C. Benztropine (Cogentin): Benztropine is an anticholinergic medication used to treat extrapyramidal symptoms (EPS), such as involuntary muscle spasms, caused by antipsychotic medications like prochlorperazine2.

D. Diphenhydramine (Benadryl): Diphenhydramine is an antihistamine with anticholinergic properties that can also be used to manage EPS, including dystonic reactions2.

Correct Answer is A

Explanation

A. "I will take both aluminum hydroxide (Amphojel) and cimetidine (Tagamet HB) at the same time." – This is correct. Taking aluminum hydroxide and cimetidine simultaneously reduces the effectiveness of cimetidine by impairing its absorption. This statement indicates a need for further teaching.

B. "I will take aluminum hydroxide (Amphojel) 1 hour before taking cimetidine (Tagamet HB)." – This is incorrect. Taking aluminum hydroxide 1 hour before cimetidine allows enough time for the antacid's effects on stomach acidity to stabilize, reducing interference.

C. "I can take aluminum hydroxide (Amphojel) 2 hours before taking cimetidine (Tagamet HB)." – This is incorrect. Taking the antacid 2 hours before cimetidine provides sufficient time for proper absorption of the medication.

D. None of the above – This is incorrect because statement A reflects improper administration.

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