A nurse is caring for an infant whose screening test reveals a potential diagnosis of sickle cell disease. Which of the following tests should the nurse expect the provider to prescribe to distinguish whether the infant has sickle cell disease or sickle cell trait?

A. Hoarseness: Hoarseness is a common symptom of croup and is usually not an immediate concern unless accompanied by other severe symptoms.

B. Barky cough: A barky cough is characteristic of croup and is not an indication of immediate concern unless it worsens.

C. Drooling: Drooling can be a sign of respiratory distress and difficulty swallowing, which can indicate a worsening condition such as epiglottitis, a more serious infection that can occur with croup. Drooling is a red flag and requires immediate medical attention.

D. Paroxysmal attacks of laryngeal spasm at night: Paroxysmal attacks (episodes of severe coughing or difficulty breathing) are typical of croup, especially at night, but are usually self-limited and not an immediate cause for concern unless severe.

A. Used in the treatment of cystic fibrosis to help break up thick secretions: Prednisone is not used to treat cystic fibrosis. Drugs like dornase alfa are used for this purpose, not corticosteroids.

B. Used for the prophylactic treatment of asthma/allergies: Prednisone is not typically used for the prophylaxis of asthma or allergies. It may be used for acute exacerbations but is not for long-term control.

C. Used to treat hypertension and edema: Prednisone is not used to treat hypertension or edema directly. Corticosteroids like prednisone can sometimes increase blood pressure and cause fluid retention as side effects.

D. Used to treat inflammation and swelling: Prednisone is a corticosteroid used to reduce inflammation and swelling in conditions such as asthma, arthritis, and other inflammatory disorders.