A nurse is caring for an infant whose screening test reveals a potential diagnosis of sickle cell disease. Which of the following tests should the nurse expect the provider to prescribe to distinguish whether the infant has sickle cell disease or sickle cell trait?
Transcranial doppler
Sickle solubility test
Complete blood count
Hemoglobin electrophoresis
The Correct Answer is D
A. Transcranial doppler: This test is used to assess blood flow in the brain and is often used for children with sickle cell disease to evaluate the risk of stroke. It is not used to distinguish between sickle cell disease and trait.
B. Sickle solubility test: This test is used to identify sickling in red blood cells, which can indicate sickle cell disease, but it does not differentiate between sickle cell disease and sickle cell trait.
C. Complete blood count (CBC): While a CBC can provide information about anemia and red blood cell characteristics, it cannot differentiate between sickle cell disease and sickle cell trait.
D. Hemoglobin electrophoresis: This test is the gold standard for diagnosing sickle cell disease and trait. It separates different types of hemoglobin based on their electrical charge, allowing for the identification of hemoglobin S (sickle hemoglobin), which distinguishes between sickle cell disease (homozygous) and sickle cell trait (heterozygous).
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Related Questions
Correct Answer is C
Explanation
A. Initiate a 2 L/day fluid restriction: Fluid intake should be increased, not restricted, during a sickle cell crisis to help prevent dehydration and improve circulation.
B. Encourage exercise: Exercise is not recommended during a sickle cell crisis as it can worsen symptoms and lead to more complications.
C. Assist with administering a blood transfusion: Blood transfusions are a common treatment during a sickle cell crisis to help increase the number of healthy red blood cells and decrease the risk of further complications.
D. Withhold opioids to avoid dependence: Pain management is essential in a sickle cell crisis, and withholding opioids could lead to unnecessary suffering. Opioids should be given based on the severity of the pain.
Correct Answer is A
Explanation
A. Squatting increases the return of venous blood flow to the heart: Squatting increases systemic vascular resistance and venous return, which helps to increase oxygenation in children with Tetralogy of Fallot, as it reduces the right-to-left shunting and increases blood flow to the lungs.
B. Squatting in common resting position when a child is tachycardic: While squatting can be used to manage symptoms, this answer is misleading as squatting specifically helps in increasing blood flow and decreasing the symptoms of cyanosis in Tetralogy of Fallot, not just during tachycardia.
C. Squatting decreases arterial blood flow away from the heart: Squatting actually increases blood flow to the heart and lungs by increasing systemic vascular resistance.
D. Squatting increases the workload of the heart: Squatting helps reduce the workload on the heart in Tetralogy of Fallot by improving oxygenation and decreasing cyanosis.
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