A nurse is caring for four clients who have peptic ulcer disease.
The nurse should recognize that misoprostol is contraindicated for which of the following clients?
A client who is receiving long-term NSAID therapy.
A client who might be pregnant.
A client who has a gastrointestinal bleed.
A client who is experiencing diarrhea.
The Correct Answer is B
Choice A rationale
Misoprostol is indicated to prevent NSAID-induced gastric ulcers due to its cytoprotective properties. It increases mucus and bicarbonate production, protecting the stomach lining without contraindications for long-term NSAID therapy.
Choice B rationale
Misoprostol is contraindicated in pregnancy due to its uterotonic effects, which can cause uterine contractions and potentially lead to miscarriage or preterm labor, posing significant risks to the fetus and pregnancy.
Choice C rationale
Misoprostol is used for gastrointestinal protection and is not contraindicated for clients with a GI bleed. It can aid in preventing further mucosal damage and promoting healing in the gastrointestinal tract.
Choice D rationale
Misoprostol can cause diarrhea as a side effect but is not contraindicated. Management of diarrhea involves supportive care and dose adjustment rather than discontinuation of the medication unless symptoms are severe.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale
Contact lenses should be removed before administering eye drops to avoid absorption of the medication into the lens, which can cause irritation and decrease effectiveness.
Choice B rationale
Brimonidine may cause ocular irritation upon instillation due to its vasoconstrictive properties, which reduce intraocular pressure by decreasing aqueous humor production. Normal intraocular pressure is 12-22 mmHg.
Choice C rationale
Brimonidine is a chronic therapy for open-angle glaucoma, requiring long-term use to maintain intraocular pressure within normal range and prevent optic nerve damage.
Choice D rationale
Brimonidine does not typically cause iris pigmentation changes. Prostaglandin analogs, like latanoprost, may alter eye color by increasing melanin content in iris stromal melanocytes.
Correct Answer is A
Explanation
Choice A rationale
Increasing fluid intake helps counteract the anticholinergic effects of amitriptyline, such as dry mouth and constipation, by maintaining adequate hydration and promoting gastrointestinal motility.
Choice B rationale
Amitriptyline commonly causes orthostatic hypotension rather than an elevation in blood pressure, particularly in the initial stages of treatment.
Choice C rationale
Orange urine discoloration is not a typical side effect of amitriptyline and does not necessitate stopping the medication; it is not a common adverse effect.
Choice D rationale
Taking amitriptyline in the morning is not recommended due to its sedative effects, which can cause daytime drowsiness and impair daily activities; it is better taken at bedtime. .
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