A nurse is discussing the role of the cystic fibrosis transmembrane conductance regulator (CFTR) protein with a patient. What is the primary function of the CFTR protein in normal physiology?

"The CFTR protein regulates sodium absorption in the kidneys."

"The CFTR protein facilitates chloride secretion in the gastrointestinal tract."

"The CFTR protein controls the production of red blood cells in the bone marrow."

"The CFTR protein regulates mucus production and the movement of chloride ions in the respiratory and digestive systems."

Answer and Explanation

The Correct Answer is D

A) Incorrect. The CFTR protein primarily functions in the respiratory and digestive systems, not the kidneys.

B) Incorrect. While CFTR plays a role in chloride secretion, its primary role is related to mucus production and chloride ion movement in the respiratory and digestive systems.

C) Incorrect. The CFTR protein is not involved in the production of red blood cells.

D) Correct. The CFTR protein is responsible for regulating mucus consistency and chloride ion transport in the respiratory and digestive systems.

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Correct Answer is C

Explanation

A) Incorrect. PERT is not primarily used to control blood sugar levels; it is used to improve nutrient absorption.

B) Incorrect. While CF management aims to improve lung function, PERT is specifically used to address pancreatic insufficiency and digestive issues.

C) Correct. The primary purpose of PERT in CF management is to replace the missing digestive enzymes and aid in the digestion of fats and nutrients.

D) Incorrect. PERT does not increase mucus production in the airways; it is focused on the digestive system.

A. "CF is caused by an extra chromosome, leading to genetic imbalance." B. "In CF, there is a duplication of the CFTR gene on chromosome 7." C. "CF results from a mutation in the CFTR gene, which codes for a dysfunctional chloride channel." D. "CF is characterized by the absence of the CFTR gene in affected individuals."

Correct Answer is C

Explanation

A) Incorrect. CF is not caused by an extra chromosome; it is a genetic disorder resulting from mutations in specific genes.

B) Incorrect. CF is not characterized by a duplication of the CFTR gene but rather by various mutations in this gene.

C) Correct. CF is primarily caused by mutations in the CFTR (cystic fibrosis transmembrane conductance regulator) gene, leading to the production of dysfunctional chloride channels.

D) Incorrect. CF is not characterized by the absence of the CFTR gene; instead, it involves various mutations in this gene.

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A nurse is discussing the role of the cystic fibrosis transmembrane conductance regulator (CFTR) protein with a patient. What is the primary function of the CFTR protein in normal physiology?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is discussing pancreatic enzyme replacement therapy (PERT) with a client who has cystic fibrosis (CF). What should the nurse emphasize as the purpose of PERT in CF management?

Correct Answer is C

Explanation

A nurse is discussing the underlying genetic defect in cystic fibrosis (CF) with a client. Which of the following statements accurately describes the primary genetic abnormality in CF?

Correct Answer is C

Explanation

A client with suspected cystic fibrosis (CF) is undergoing diagnostic testing. What diagnostic procedure is often used to confirm CF by analyzing the genetic mutations present?

A nurse is discussing the role of genetic testing in cystic fibrosis (CF) diagnosis with a client. What should the nurse emphasize regarding the importance of genetic testing for CF?

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A nurse is counseling a couple planning to start a family, and both partners have a family history of cystic fibrosis (CF). What should the nurse advise the couple regarding the genetic risk of having a child with CF?

A client is inquiring about the genetic basis of cystic fibrosis (CF). Which statement by the nurse provides an accurate explanation?

A nurse is discussing the clinical manifestations of cystic fibrosis (CF) with a newly diagnosed adolescent client. What common respiratory symptom should the nurse emphasize as an early sign of CF?

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