A nurse is discussing the role of the cystic fibrosis transmembrane conductance regulator (CFTR) protein with a patient. What is the primary function of the CFTR protein in normal physiology?

"The CFTR protein regulates sodium absorption in the kidneys."

"The CFTR protein facilitates chloride secretion in the gastrointestinal tract."

"The CFTR protein controls the production of red blood cells in the bone marrow."

"The CFTR protein regulates mucus production and the movement of chloride ions in the respiratory and digestive systems."

Answer and Explanation

The Correct Answer is D

A) Incorrect. The CFTR protein primarily functions in the respiratory and digestive systems, not the kidneys.

B) Incorrect. While CFTR plays a role in chloride secretion, its primary role is related to mucus production and chloride ion movement in the respiratory and digestive systems.

C) Incorrect. The CFTR protein is not involved in the production of red blood cells.

D) Correct. The CFTR protein is responsible for regulating mucus consistency and chloride ion transport in the respiratory and digestive systems.

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Correct Answer is B

Explanation

A) Incorrect. Frequent nosebleeds are not a hallmark symptom of CF.

B) Correct. A chronic cough with thick, sticky mucus production is a hallmark feature of CF due to the accumulation of mucus in the respiratory tract.

C) Incorrect. Rapid weight gain is not a typical symptom of CF; in fact, individuals with CF often struggle with poor weight gain and malnutrition.

D) Incorrect. High blood pressure is not a characteristic symptom of CF.

A. "CF is caused by a dominant genetic mutation that always manifests in affected individuals." B. "CF results from the presence of two recessive genetic mutations, one inherited from each parent." C. "CF is due to a spontaneous genetic mutation that occurs during a person's lifetime." D. "CF is exclusively caused by environmental factors and is not related to genetics."

Correct Answer is B

Explanation

A) Incorrect. CF is an autosomal recessive genetic disorder, meaning that both copies of the CFTR gene must carry a mutation for the condition to manifest.

B) Correct. CF is caused by the inheritance of two recessive genetic mutations, one from each parent, resulting in defective CFTR protein function.

C) Incorrect. CF is primarily a genetic disorder present from birth, not one caused by spontaneous mutations during a person's lifetime.

D) Incorrect. CF is primarily a genetic disorder with well-established genetic mutations associated with its development.

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A nurse is discussing the role of the cystic fibrosis transmembrane conductance regulator (CFTR) protein with a patient. What is the primary function of the CFTR protein in normal physiology?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is explaining the typical clinical manifestations of cystic fibrosis (CF) to a newly diagnosed adolescent client. Which symptom should the nurse emphasize as a hallmark of CF?

Correct Answer is B

Explanation

A client is inquiring about the genetic basis of cystic fibrosis (CF). Which statement by the nurse provides an accurate explanation?

Correct Answer is B

Explanation

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