A nurse is educating a client about the etiology of cystic fibrosis (CF). Which statement by the client accurately describes the genetic basis of CF?

"CF is caused by a single gene mutation, which can be inherited from one parent."

"CF results from a combination of genetic and environmental factors."

"CF occurs due to an X-linked genetic mutation passed from mother to daughter."

"CF is primarily caused by exposure to respiratory pathogens during infancy."

Answer and Explanation

The Correct Answer is A

A) Correct. CF is primarily caused by mutations in a single gene, the CFTR gene, and it can be inherited from one parent, resulting in a carrier state, or from both parents for the disease to manifest.

B) Incorrect. While genetic factors are the primary cause of CF, environmental factors can exacerbate symptoms but are not the root cause.

C) Incorrect. CF is not an X-linked genetic disorder; it follows an autosomal recessive pattern of inheritance.

D) Incorrect. CF is not caused by exposure to respiratory pathogens during infancy; it is primarily a genetic disorder.

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Correct Answer is B

Explanation

A) Incorrect. CF primarily affects the lower respiratory tract, particularly the bronchi and bronchioles, rather than the upper respiratory tract.

B) Correct. CF leads to thickened mucus in the airways, which can cause inflammation, recurrent infections, and progressive lung damage.

C) Incorrect. Enlarged tonsils and adenoids are not a typical manifestation of CF-related respiratory complications.

D) Incorrect. CF affects both the bronchial tubes and the entire respiratory system, often leading to chronic lung infections.

A. "CF is more common in females than males." B. "Being of African descent significantly increases the risk of developing CF." C. "A family history of CF is a risk factor, as it increases the likelihood of inheriting the mutated gene." D. "CF is unrelated to ethnicity, and anyone can be equally affected."

Correct Answer is C

Explanation

A) Incorrect. CF occurs at a similar frequency in both males and females.

B) Incorrect. CF is not significantly associated with any specific ethnicity, and the risk is not influenced by being of African descent.

C) Correct. A family history of CF increases the risk because CF is an autosomal recessive genetic disorder, and having affected family members increases the likelihood of carrying CF gene mutations.

D) Incorrect. While CF can affect individuals from any ethnicity, it is primarily a genetic disorder, and family history plays a crucial role in the risk of inheritance.

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A nurse is educating a client about the etiology of cystic fibrosis (CF). Which statement by the client accurately describes the genetic basis of CF?

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Naxlex Comprehensive Predictor Exams

A client with cystic fibrosis (CF) asks the nurse about the impact of CF on the respiratory system. What response by the nurse accurately describes the respiratory complications associated with CF?

Correct Answer is B

Explanation

A nurse is discussing the risk factors for cystic fibrosis (CF) with a client. Which statement accurately identifies a risk factor associated with CF?

Correct Answer is C

Explanation

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