A nurse is educating a group of travelers who are going to a region where malaria is endemic.
Which of the following antimalarial drugs should the nurse recommend for prophylaxis? (Select all that apply.).
Quinine
Primaquine
Mefloquine
Pyrimethamine-sulfadiazine
Atovaquone-proguanil.
Correct Answer : C,D,E
These are the antimalarial drugs that are recommended for prophylaxis by the CDC and other sources.
They are effective against the malaria parasites that are resistant to chloroquine and primaquine, which are the other two options.
Choice A is wrong because chloroquine is not effective in areas where chloroquine resistance is present, which is most of the malaria-endemic regions.
Choice B is wrong because primaquine is not used for prophylaxis, but for radical cure of vivax and ovale malaria. It also requires a test for glucose-6-phosphate dehydrogenase (G6PD) deficiency before use, as it can cause hemolysis in people with this condition.
Choice C is correct because mefloquine is a suppressive prophylactic that can be used in areas with chloroquine resistance.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
This statement indicates a need for further teaching because linezolid should be taken for the full prescribed course of treatment, even if the symptoms improve or resolve.Stopping the medication too soon can lead to bacterial resistance or recurrence of the infection.
Choice A is wrong because it is a correct statement.Linezolid can cause optic neuropathy or vision changes, so patients should report any changes in their vision to their doctor.
Choice B is wrong because it is a correct statement.
Linezolid can interact with foods that contain tyramine, such as cheese and red wine, and cause a hypertensive crisis.Patients should avoid eating foods that contain tyramine while taking linezolid and for two weeks after stopping the medication.
Choice C is wrong because it is a correct statement.Linezolid can be taken with or without food, but taking it on an empty stomach may help with absorption and effectiveness.
Correct Answer is ["D","E"]
Explanation
A microbe acquires antibiotic resistance by transferring DNA coding to other bacteria or by spontaneous mutation in the microbial genome.
These genetic changes allow the microbe to survive the effects of the antibiotic and pass on the resistance to its offspring.
ChoiceAis wrong because the host does not develop medication resistance, but the microbe does.
ChoiceBis wrong because the minimum bactericidal concentration (MBC) is the lowest concentration of an antibiotic needed to kill 99.9% of bacteria, not a mechanism of resistance.
ChoiceCis wrong because incorrect dosing does not cause ribosome mutations, but may promote the emergence of drug-resistant microbes by exposing them to suboptimal levels of the antibiotic.
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