A nurse is educating a group of travelers who are going to a region where malaria is endemic.
Which of the following antimalarial drugs should the nurse recommend for prophylaxis? (Select all that apply.).
Quinine
Primaquine
Mefloquine
Pyrimethamine-sulfadiazine
Atovaquone-proguanil.
Correct Answer : C,D,E
These are the antimalarial drugs that are recommended for prophylaxis by the CDC and other sources.
They are effective against the malaria parasites that are resistant to chloroquine and primaquine, which are the other two options.
Choice A is wrong because chloroquine is not effective in areas where chloroquine resistance is present, which is most of the malaria-endemic regions.
Choice B is wrong because primaquine is not used for prophylaxis, but for radical cure of vivax and ovale malaria. It also requires a test for glucose-6-phosphate dehydrogenase (G6PD) deficiency before use, as it can cause hemolysis in people with this condition.
Choice C is correct because mefloquine is a suppressive prophylactic that can be used in areas with chloroquine resistance.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["B","D"]
Explanation
Flucytosine can cause bone marrow suppression and renal toxicity, so the nurse should monitor the client’s renal function tests and complete blood count before giving this medication.
These tests can help detect any signs of anemia, leukopenia, thrombocytopenia, or impaired kidney function that may require dose adjustment or discontinuation of the drug.
Choice A is wrong because flucytosine does not affect liver function significantly.Choice C is wrong because flucytosine does not cause changes in blood pressure.Choice E is wrong because flucytosine does not affect cardiac function or cause arrhythmias.
Correct Answer is ["C","D","E"]
Explanation
These are the antimalarial drugs that are recommended for prophylaxis by the CDC and other sources.
They are effective against the malaria parasites that are resistant to chloroquine and primaquine, which are the other two options.
Choice A is wrong because chloroquine is not effective in areas where chloroquine resistance is present, which is most of the malaria-endemic regions.
Choice B is wrong because primaquine is not used for prophylaxis, but for radical cure of vivax and ovale malaria.It also requires a test for glucose-6-phosphate dehydrogenase (G6PD) deficiency before use, as it can cause hemolysis in people with this condition.
Choice C is correct because mefloquine is a suppressive prophylactic that can be used in areas with chloroquine resistance.
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