A nurse is caring for a client who is receiving gentamicin, an aminoglycoside antibiotic, for a severe infection.
The nurse should monitor the client for which adverse effects of this drug? (Select all that apply.)
Ototoxicity
Nephrotoxicity
Hepatotoxicity
Neuromuscular blockade
Thrombocytopenia.
Correct Answer : A,B
Gentamicin is an aminoglycoside antibiotic that can cause ototoxicity (damage to the inner ear) and nephrotoxicity (damage to the kidneys) as serious side effects. These effects may be irreversible and can occur even at therapeutic doses. Therefore, the nurse should monitor the client’s hearing, balance, urine output, and blood tests for kidney function while on this drug.
Choice C is wrong because gentamicin does not cause hepatotoxicity (damage to the liver).
This is more common with other antibiotics such as isoniazid or rifampin.
Choice D is wrong because gentamicin does not cause neuromuscular blockade (paralysis of muscles).
This is more common with other aminoglycosides such as neomycin or tobramycin.
Choice E is wrong because gentamicin does not cause thrombocytopenia (low platelet count).
This is more common with other drugs such as heparin or sulfonamides.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A Mazzotti reaction is a severe inflammatory response that can occur after taking ivermectin for onchocerciasis (river blindness), a parasitic infection caused by Onchocerca volvulus.The reaction is due to the death of the microfilariae (larvae) of the parasite and can cause fever, rash, itching, joint pain, swollen lymph nodes, and eye inflammation.
Choice A is wrong because hypertension is not a common adverse effect of ivermectin.Hypotension, however, can occur in some cases.
Choice B is wrong because tinnitus is not a common adverse effect of ivermectin.Tinnitus is a ringing or buzzing sound in the ears that can be caused by various factors, such as exposure to loud noise, ear infections, or certain medications.
Choice D is wrong because Stevens-Johnson syndrome is not a common adverse effect of ivermectin.
Stevens-Johnson syndrome is a rare but serious skin reaction that can be triggered by infections or medications.
It causes blisters and peeling of the skin and mucous membranes.
Correct Answer is C
Explanation
Ceftriaxone belongs to the third-generation of cephalosporins.Third-generation cephalosporins have greater activity than the second-generation cephalosporins against certain gram-negative bacteria, such as Streptococcus pneumoniae.They are also more resistant to beta-lactamases, enzymes that can inactivate some cephalosporins.
Choice A is wrong because first-generation cephalosporins have less activity against gram-negative bacteria and are more susceptible to beta-lactamases.
Choice B is wrong because second-generation cephalosporins have less activity against Streptococcus pneumoniae than third-generation cephalosporins, and are also less resistant to beta-lactamases.
Choice D is wrong because fourth-generation cephalosporins have a broader spectrum of activity against gram-negative bacteria, including some that are resistant to third-generation cephalosporins, but they are not more effective against Streptococcus pneumoniae.
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