A nurse is caring for a client who is receiving gentamicin, an aminoglycoside antibiotic, for a severe infection.
The nurse should monitor the client for which adverse effects of this drug? (Select all that apply.)

Ototoxicity

Nephrotoxicity

Hepatotoxicity

Neuromuscular blockade

Thrombocytopenia.

Answer and Explanation

Correct Answer : A,B

Gentamicin is an aminoglycoside antibiotic that can cause ototoxicity (damage to the inner ear) and nephrotoxicity (damage to the kidneys) as serious side effects. These effects may be irreversible and can occur even at therapeutic doses. Therefore, the nurse should monitor the client’s hearing, balance, urine output, and blood tests for kidney function while on this drug.

Choice C is wrong because gentamicin does not cause hepatotoxicity (damage to the liver).

This is more common with other antibiotics such as isoniazid or rifampin.

Choice D is wrong because gentamicin does not cause neuromuscular blockade (paralysis of muscles).

This is more common with other aminoglycosides such as neomycin or tobramycin.

Choice E is wrong because gentamicin does not cause thrombocytopenia (low platelet count).

This is more common with other drugs such as heparin or sulfonamides.

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Correct Answer is ["B","C","D"]

Explanation

Choice A is wrong because azithromycin (Zithromax) should be takenwith foodto prevent stomach upset.

Choice B is correct because azithromycin can causeliver damageand the client should report any signs ofjaundiceordark urineas they may indicate liver problems.

Choice C is correct because azithromycin can interact withgrapefruit juiceand increase the risk ofside effectssuch as nausea, vomiting, diarrhea, headache and QT interval prolongation.

Choice D is correct because the client shouldcomplete the full course of therapyas prescribed to prevent bacterial resistance and recurrence of infection.

Choice E is wrong because azithromycin should be stored in arefrigeratorand discarded after 10 days if it is in a liquid form.

A. Tinnitus B. Vertigo C. Hearing loss D. All of the above.

Correct Answer is D

Explanation

Vancomycin is an antibiotic that can cause ototoxicity, which is damage to the inner ear due to exposure to certain drugs.Ototoxicity can manifest as tinnitus (ringing in the ears), vertigo (dizziness), and hearing loss.Vancomycin ototoxicity is usually related to high serum levels of the drug and is more likely to occur in patients with renal impairment.Vancomycin can also potentiate the ototoxicity of other drugs, such as aminoglycosides.

Choice A is wrong because tinnitus is a possible manifestation of ototoxicity.

Choice B is wrong because vertigo is a possible manifestation of ototoxicity.

Choice C is wrong because hearing loss is a possible manifestation of ototoxicity.

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A nurse is caring for a client who is receiving gentamicin, an aminoglycoside antibiotic, for a severe infection. The nurse should monitor the client for which adverse effects of this drug? (Select all that apply.)

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is educating a client who has a respiratory infection and a new prescription for azithromycin (Zithromax). Which of the following instructions should the nurse include? (Select all that apply).

Correct Answer is ["B","C","D"]

Explanation

A nurse is caring for a client who has a severe infection and is receiving vancomycin (Vancocin). The nurse should monitor the client for which of the following manifestations of ototoxicity?

Correct Answer is D

Explanation

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A nurse is caring for a client who is receiving gentamicin, an aminoglycoside antibiotic, for a severe infection.
The nurse should monitor the client for which adverse effects of this drug? (Select all that apply.)