After reviewing information about lincosamide therapy, a group of nursing students demonstrate understanding of the information when they identify which of the following as a contraindication?

Choice A rationale:

Pseudomembranous colitis Pseudomembranous colitis is a severe inflammation of the colon that can be caused by the overgrowth of Clostridium difficile, often associated with antibiotic use. Antidiarrheal drugs should not be administered in cases of infectious diarrhea, as they can worsen the condition. The nurse should be alert to this contraindication to avoid potential harm to the client.

Choice B rationale:

Type 1 diabetes Type 1 diabetes is not typically a contraindication for antidiarrheal drug use. However, it is essential to consider the overall health of the client and the potential causes of their diarrhea. In some cases, diabetes-related issues could be relevant, but it is not a direct contraindication for antidiarrheal drugs.

Choice C rationale:

Liver disease Liver disease is not a direct contraindication for antidiarrheal drug use. While the liver plays a role in drug metabolism, antidiarrheal drugs primarily affect the gastrointestinal system and do not directly harm the liver. However, individual patient factors and liver function should be considered.

Choice D rationale:

Renal Disease Renal disease is not typically a contraindication for antidiarrheal drug use. These drugs primarily affect the gastrointestinal system and do not have a direct impact on the kidneys. However, in patients with severe renal disease, it is essential to consider their overall health and the potential causes of their diarrhea.

Choice A rationale:

Sulfonamides can increase the risk of crystalluria, which may lead to kidney stones. Adequate fluid intake can help dilute the urine and reduce the risk of crystalluria and kidney stone formation. This is a relevant and appropriate response by the nurse.

Choice B rationale:

Sulfonamides can make the skin more sensitive to sunlight, increasing the risk of sunburn. However, increasing fluid intake is primarily to prevent kidney stone formation, not a reaction to sunlight.

Choice C rationale:

While maintaining adequate hydration does help prevent dehydration, this answer does not directly address the potential side effects or risks associated with sulfonamide use. It is a bit too general and doesn't provide specific information related to the medication.

Choice D rationale:

Sulfonamides can affect blood counts in some cases, but maintaining adequate fluid intake is not primarily related to preventing low blood counts. It's more about mitigating the specific side effects associated with sulfonamide use, such as crystalluria and kidney stones.