A patient has had an overdose of an intravenous cholinergic drug. The nurse expects to administer which drug as an antidote?

Dobutamine

Atropine sulfate

Atenolol

Bethanechol

Answer and Explanation

The Correct Answer is B

A.   Dobutamine is a sympathomimetic drug used to increase cardiac output in conditions such as heart failure. It is not an antidote for cholinergic drug overdose.
B.   Atropine sulfate is the antidote for cholinergic drug overdose. It acts as a competitive antagonist to acetylcholine at muscarinic receptors, counteracting the effects of excessive cholinergic stimulation.
C.   Atenolol is a beta-blocker used to manage hypertension and certain cardiac conditions. It is not an antidote for cholinergic drug overdose.
D.   Bethanechol is a cholinergic agonist used to stimulate bladder contractions in urinary retention. It is not an antidote for cholinergic drug overdose; in fact, it would exacerbate cholinergic effects.

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Correct Answer is B

Explanation

A. Signs of bone marrow depression are not typically associated with antiepileptic drugs. This adverse effect is more commonly seen with medications such as chemotherapy agents.
B. Increased risk of suicidal thoughts and behaviors is a well-documented concern with antiepileptic drugs, particularly when used for psychiatric indications or in certain patient populations. The FDA has issued warnings regarding this risk, and healthcare providers should monitor patients for changes in mood, behavior, and suicidal ideation.
C. While some antiepileptic drugs may have cardiovascular effects, such as prolongation of the QT interval, the FDA warning specifically highlights the risk of suicidal thoughts and behaviors rather than cardiovascular events like strokes.

D. Indications of drug addiction and dependency are not typically associated with antiepileptic drugs. These medications are not central nervous system depressants and do not produce the euphoria or withdrawal symptoms characteristic of addictive substances.

Correct Answer is ["0.5"]

Explanation

Given:

Dose required = 35 mg

Concentration of medication = 75 mg/mL Formula:

Volume (mL) = Dose required (mg) / Concentration of medication (mg/mL) Calculation:

Volume (mL) = 35 mg / 75 mg/mL Result:

Volume (mL) = 0.4666667 mL Rounded to the nearest tenth:

Volume (mL) ≈ 0.5 mL

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A patient has had an overdose of an intravenous cholinergic drug. The nurse expects to administer which drug as an antidote?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

The U.S. Food and Drug Administration has issued a warning for users of antiepileptic drugs. Based on this report, the nurse will monitor for which potential problems with this class of drugs?

Correct Answer is B

Explanation

A nurse is preparing to administer meperidine 35 mg IM to a client every 6 hr PRN for pain. Available is meperidine injection 75 mg/mL. How many mL should the nurse administer per dose? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

Correct Answer is ["0.5"]

Explanation

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