A provider has ordered oral voriconazole [Vfend] which is an azole medication for a patient who has a systemic fungal infection. The nurse obtains a medication history and learns that the patient takes anticoagulant medication Warfarin. The nurse will contact the provider to discuss which possibility?

Choice C reason: Abdominal distention and hypogastric pain are classic signs and symptoms of large bowel obstruction. The obstruction prevents the normal passage of intestinal contents, leading to a buildup of gas and fluid, which causes distention and pain.
Choice A reason: Epigastric pain and rectal bleeding are not typical signs of large bowel obstruction. These symptoms are more commonly associated with other gastrointestinal conditions, such as peptic ulcers or colorectal cancer.
Choice B reason: Fluid overload and passing gas are not characteristic of large bowel obstruction. In fact, the inability to pass gas is a common symptom of bowel obstruction.
Choice D reason: Diarrhea and excessive thirst are not typical signs of large bowel obstruction. Diarrhea is more commonly associated with conditions affecting the small intestine or infections, while excessive thirst is a symptom of dehydration or diabetes.

Choice A reason:
An embolus is the term used to describe a detached blood clot or other material that travels through the bloodstream and can cause a blockage in a blood vessel. Emboli can be composed of blood clots, fat, air, or other substances, and they can lead to serious conditions like strokes or pulmonary embolisms when they obstruct blood flow.

Choice B reason:
A thrombus is a blood clot that forms in a blood vessel and remains at its site of origin. It does not refer to a clot that has detached and is traveling through the bloodstream. The distinction between thrombus and embolus is crucial in understanding and describing vascular conditions.

Choice C reason:
Thromboembolus is a term that combines thrombus and embolus, indicating that a thrombus has become an embolus. While accurate, the more precise and commonly used term for a detached blood clot is simply "embolus."

Choice D reason:
Infarction refers to tissue death due to a lack of blood supply, often caused by an embolus or thrombus blocking a blood vessel. It does not describe the detached blood clot itself but rather the result of its action.